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Journal of Medicinal Chemistry|January 16, 2019
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 InhibitorsKatharina Vögerl, Nghia Ong, Johanna Senger, et al.Nature Communications|May 14, 2016
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugsAlexander Karlas, Stefano Berre, Thérèse Couderc, et al.Iscience|May 21, 2024
DHCR24 inhibitor SH42 increases desmosterol without preventing atherosclerosis development in miceXiaoke Ge, Bram Slütter, Joost M Lambooij, et al.Nature Communications|August 2, 2022
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomesYu Yuan, Dawid Jaślan, Taufiq Rahman, et al.Nature Communications|June 10, 2026
O-linked glycan-dependent gating of TPC2 controls lysosomal excitability and organelle remodelingAlice Lin, Neng-Yu Lin, Marco Keller, et al.Journal of Endocrinological Investigation|May 6, 2026
Inhibition of endolysosomal two-pore channel 2 (TPC2) induces osteoblast differentiation and matrix mineralization while targeting autophagyAzadeh Montaseri, Michela Rossi, Giulia Battafarano, et al.Cell Reports|December 1, 2023
P-selectin-dependent leukocyte adhesion is governed by endolysosomal two-pore channel 2Jonas Goretzko, Inga Pauels, Nicole Heitzig, et al.EMBO Molecular Medicine|June 26, 2023
Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammationEnchen Zhou, Xiaoke Ge, Hiroyuki Nakashima, et al.ACS Chemical Biology|May 9, 2025
Serendipitous and Systematic Chemoproteomic Discovery of MBLAC2, HINT1, and NME1-4 Inhibitors from Histone Deacetylase-Targeting PharmacophoresSeverin Lechner, Shuyao Sha, Jigar Paras Sethiya, et al.Cellular and Molecular Life Sciences : CMLS|February 22, 2025
Inhibition of DYRK1B BY C81 impedes inflammatory processes in leukocytes by reducing STAT3 activitySarah Ciurus, Mohammed A F Elewa, Megan A Palmer, et al.Pageof 18