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DNA Repair|July 3, 2020
TREX1 - Apex predator of cytosolic DNA metabolismSean R Simpson, Wayne O Hemphill, Teesha Hudson, et al.
Cell Cycle (Georgetown, Tex.)|February 10, 2015
Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H bindingRyan R Davis, Nadine M Shaban, Fred W Perrino, et al.
The Journal of Biological Chemistry|November 10, 2011
Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolaseRebecca D Powell, Paul J Holland, Thomas Hollis, et al.
The Journal of Biological Chemistry|September 23, 2011
The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activityClinton D Orebaugh, Jason M Fye, Scott Harvey, et al.
The Journal of Biological Chemistry|September 23, 2008
The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune diseaseDuane A Lehtinen, Scott Harvey, Matthew J Mulcahy, et al.
The Journal of Biological Chemistry|August 3, 2011
Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndromeJason M Fye, Clinton D Orebaugh, Stephanie R Coffin, et al.
The Journal of Biological Chemistry|March 12, 2014
The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomersJason M Fye, Stephanie R Coffin, Clinton D Orebaugh, et al.
DNA Repair|October 19, 2010
Bypass of N²-ethylguanine by human DNA polymerase κMatthew G Pence, Patrick Blans, Charles N Zink, et al.
Chemical Research in Toxicology|September 20, 2005
Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alphaFred W Perrino, Scott Harvey, Patrick Blans, et al.
The Journal of Biological Chemistry|February 13, 2007
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partneringUdesh de Silva, Sumana Choudhury, Suzanna L Bailey, et al.
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