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Frederic Cumin

Showing results (1-10 of 20) with videos related to

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Current Pharmaceutical Design|February 23, 2007
Aspartic proteases in drug discoveryJörg Eder, Ulrich Hommel, Frederic Cumin, et al.
Journal of Hypertension|January 22, 2005
Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive ratsJeanette M Wood, Christian R Schnell, Frederic Cumin, et al.
Bioorganic & Medicinal Chemistry Letters|March 19, 2015
trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: prime site exploration using an amino linkerEdwige Lorthiois, Frederic Cumin, Claus Ehrhardt, et al.
Journal of Biomolecular Screening|February 4, 2014
Fluorescence Lifetime-Based Competitive Binding Assays for Measuring the Binding Potency of Protease Inhibitors In VitroAndreas Boettcher, Nathalie Gradoux, Edwige Lorthiois, et al.
ACS Medicinal Chemistry Letters|May 26, 2018
Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor DAnna Vulpetti, Nils Ostermann, Stefan Randl, et al.
European Journal of Biochemistry|March 5, 2002
Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cellsDanilo Guerini, Elisabetta Prati, Urvi Desai, et al.
Scientific Reports|June 16, 2016
Structure of neprilysin in complex with the active metabolite of sacubitrilNikolaus Schiering, Allan D'Arcy, Frederic Villard, et al.
Journal of Medicinal Chemistry|February 4, 2017
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease InhibitorsAnna Vulpetti, Stefan Randl, Simon Rüdisser, et al.
Journal of Medicinal Chemistry|February 22, 2013
The discovery of novel potent trans-3,4-disubstituted pyrrolidine inhibitors of the human aspartic protease renin from in silico three-dimensional (3D) pharmacophore searchesEdwige Lorthiois, Werner Breitenstein, Frederic Cumin, et al.
Toxicology and Applied Pharmacology|March 19, 2017
The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkeyHeidi A Schoenfeld, Tim West, Philip B Verghese, et al.
Pageof 2

Showing results (1-10 of 20) with videos related to

Sort By:
Pageof 2
Current Pharmaceutical Design|February 23, 2007
Aspartic proteases in drug discoveryJörg Eder, Ulrich Hommel, Frederic Cumin, et al.
Journal of Hypertension|January 22, 2005
Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive ratsJeanette M Wood, Christian R Schnell, Frederic Cumin, et al.
Bioorganic & Medicinal Chemistry Letters|March 19, 2015
trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: prime site exploration using an amino linkerEdwige Lorthiois, Frederic Cumin, Claus Ehrhardt, et al.
Journal of Biomolecular Screening|February 4, 2014
Fluorescence Lifetime-Based Competitive Binding Assays for Measuring the Binding Potency of Protease Inhibitors In VitroAndreas Boettcher, Nathalie Gradoux, Edwige Lorthiois, et al.
ACS Medicinal Chemistry Letters|May 26, 2018
Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor DAnna Vulpetti, Nils Ostermann, Stefan Randl, et al.
European Journal of Biochemistry|March 5, 2002
Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cellsDanilo Guerini, Elisabetta Prati, Urvi Desai, et al.
Scientific Reports|June 16, 2016
Structure of neprilysin in complex with the active metabolite of sacubitrilNikolaus Schiering, Allan D'Arcy, Frederic Villard, et al.
Journal of Medicinal Chemistry|February 4, 2017
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease InhibitorsAnna Vulpetti, Stefan Randl, Simon Rüdisser, et al.
Journal of Medicinal Chemistry|February 22, 2013
The discovery of novel potent trans-3,4-disubstituted pyrrolidine inhibitors of the human aspartic protease renin from in silico three-dimensional (3D) pharmacophore searchesEdwige Lorthiois, Werner Breitenstein, Frederic Cumin, et al.
Toxicology and Applied Pharmacology|March 19, 2017
The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkeyHeidi A Schoenfeld, Tim West, Philip B Verghese, et al.
Pageof 2