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Bioorganic Chemistry|October 25, 2024
Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer's drug candidatesRosalba Leuci, Stefan Simic, Antonio Carrieri, et al.Journal of Medicinal Chemistry|December 5, 2008
Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug designRoberta Montanari, Fulvio Saccoccia, Elena Scotti, et al.Chemmedchem|February 3, 2015
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal musclesAntonio Laghezza, Roberta Montanari, Antonio Lavecchia, et al.British Journal of Pharmacology|August 2, 2003
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1Antonella Liantonio, Annamaria De Luca, Sabata Pierno, et al.Archiv Der Pharmazie|May 28, 2024
Synthesis and in vitro cytotoxicity of benzoxazole-based PPARα/γ antagonists in colorectal cancer cell linesNazaret Moreno-Rodríguez, Antonio Laghezza, Carmen Cerchia, et al.European Journal of Medicinal Chemistry|April 24, 2022
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's diseaseLeonardo Brunetti, Rosalba Leuci, Antonio Carrieri, et al.Chemmedchem|July 28, 2020
Synthesis and Biological Evaluation of Pyrazoline and Pyrrolidine-2,5-dione Hybrids as Potential Antitumor AgentsKalpana Tilekar, Neha Upadhyay, Franz-Josef Meyer-Almes, et al.Journal of Medicinal Chemistry|May 14, 2010
Structural insight into peroxisome proliferator-activated receptor gamma binding of two ureidofibrate-like enantiomers by molecular dynamics, cofactor interaction analysis, and site-directed mutagenesisGiorgio Pochetti, Nico Mitro, Antonio Lavecchia, et al.Bioorganic Chemistry|December 15, 2020
Pharmacophore hybridization approach to discover novel pyrazoline-based hydantoin analogs with anti-tumor efficacyNeha Upadhyay, Kalpana Tilekar, Fulvio Loiodice, et al.The Journal of Biological Chemistry|January 24, 2014
LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic propertiesFederica Gilardi, Marco Giudici, Nico Mitro, et al.Pageof 9