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Chemmedchem|February 27, 2016
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization SchemeGianluigi Lauro, Paolo Tortorella, Alessia Bertamino, et al.
ACS Medicinal Chemistry Letters|May 22, 2020
Sulfonimide and Amide Derivatives as Novel PPARα Antagonists: Synthesis, Antiproliferative Activity, and Docking StudiesAlessandra Ammazzalorso, Isabella Bruno, Rosalba Florio, et al.
Toxicology and Applied Pharmacology|July 6, 2016
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatinGiulia Maria Camerino, Michela De Bellis, Elena Conte, et al.
Journal of Medicinal Chemistry|April 3, 2020
Insights into PPARγ Phosphorylation and Its Inhibition MechanismRoberta Montanari, Davide Capelli, Keiko Yamamoto, et al.
Chemmedchem|October 8, 2020
A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic EffectsSabina Yasmin, Carmen Cerchia, Vishnu Nayak Badavath, et al.
Journal of Medicinal Chemistry|February 15, 2023
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier InhibitionAntonio Laghezza, Carmen Cerchia, Massimo Genovese, et al.
ACS Medicinal Chemistry Letters|April 19, 2019
Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic SyndromeLetizia Giampietro, Antonio Laghezza, Carmen Cerchia, et al.
European Journal of Medicinal Chemistry|March 15, 2025
A new potent and selective peroxisome proliferator-activated receptor alpha partial agonist displays anti-steatotic effects In vitro and behaves as a safe hypolipidemic and hypoglycemic agent in a diabetic mouse modelAntonio Laghezza, Emanuele Falbo, Federica Gilardi, et al.
Journal of Medicinal Chemistry|December 21, 2022
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide HydrolaseFrancesca Intranuovo, Leonardo Brunetti, Pietro DelRe, et al.
Journal of Medicinal Chemistry|February 5, 2026
Development of Second-Generation Phenoxyethylpiperidines as Potent Sigma-1 Receptor Agonists with Neuroprotective Potential for Alzheimer's DiseaseFrancesco Mastropasqua, Anna Teresa Lisi, Lucie Crouzier, et al.
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