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Statistical Methods in Medical Research|March 25, 2026
Randomization and allocation procedures for master protocol trials of single-arm studiesPeter Jacko, Günter Heimann, Tom Parke
European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology|October 16, 2010
ISCTM: Implementing phase 2 dose finding adaptive clinical trialsTom Parke
Statistics in Medicine|March 11, 2003
Non-parametric estimators of a monotonic dose-response curve and bootstrap confidence intervalsMaria Dilleen, Günter Heimann, Ian Hirsch
Journal of Pharmacokinetics and Pharmacodynamics|January 12, 2026
Concentration response analyses for QT data with several active compoundsGünter Heimann, Giulia Lestini, Jochen Zisowsky
CPT: Pharmacometrics & Systems Pharmacology|May 1, 2021
Exposure-response modeling for extrapolation from adult to pediatric patients who differ with respect to prognostic factors: Application to everolimusThomas Dumortier, Günter Heimann, Martin Fink
Journal of Pharmacokinetics and Pharmacodynamics|November 15, 2025
A note on phase I interleaved versus parallel group ascending dose designs for concentration-QTc analysesGünter Heimann, Thomas Dumortier, Karin Meiser
BMC Medical Research Methodology|January 17, 2025
Why and how should we simulate platform trials? Learnings from EU-PEARLElias Laurin Meyer, Tobias Mielke, Marta Bofill Roig, et al.
Statistics in Medicine|April 16, 2015
Exact and asymptotic inference in clinical trials with small event rates under inverse samplingGünter Heimann, Mark Von Tress, Mauro Gasparini
Statistics in Medicine|March 16, 2026
Clinical Trial Simulation: Planning With the OCTAVE Framework, Implementation and Validation PrinciplesKim May Lee, Babak Choodari-Oskooei, Michael J Grayling, et al.
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