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Molecular Pharmacology|October 15, 2010
Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonistFrancois G Gervais, Nicole Sawyer, Rino Stocco, et al.The Journal of Biological Chemistry|September 29, 2000
Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domainA S Hackam, A S Yassa, R Singaraja, et al.Nature Cell Biology|January 15, 2002
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner HippiFrançois G Gervais, Roshni Singaraja, Steven Xanthoudakis, et al.Bioorganic & Medicinal Chemistry Letters|August 29, 2009
Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonistsShilan Liu, Yinhui Liu, Hongmei Wang, et al.European Journal of Pharmacology|September 28, 2014
Anti-inflammatory actions of Chemoattractant Receptor-homologous molecule expressed on Th2 by the antagonist MK-7246 in a novel rat model of Alternaria alternata elicited pulmonary inflammationMalgorzata A Gil, Michael Caniga, Janice D Woodhouse, et al.Cell|May 13, 1999
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formationF G Gervais, D Xu, G S Robertson, et al.Bioorganic & Medicinal Chemistry Letters|November 26, 2010
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseasesMichel Gallant, Christian Beaulieu, Carl Berthelette, et al.Pageof 6