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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 30, 2020
The Pharmacokinetic-Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GISTVenkatesh Pilla Reddy, Rana Anjum, Michael Grondine, et al.Bioorganic & Medicinal Chemistry Letters|October 15, 2008
Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidinesCatherine Bardelle, Tanya Coleman, Darren Cross, et al.Bioorganic & Medicinal Chemistry Letters|June 30, 2006
Inhibitors of epidermal growth factor receptor tyrosine kinase: optimisation of potency and in vivo pharmacokineticsPeter Ballard, Robert H Bradbury, Craig S Harris, et al.ACS Chemical Biology|January 5, 2023
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized HitAarti Kawatkar, Roger A Clark, Lorna Hopcroft, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 ReceptorsBernard Barlaam, Judith Anderton, Peter Ballard, et al.Journal of Medicinal Chemistry|March 5, 2015
Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesisJason G Kettle, Peter Ballard, Catherine Bardelle, et al.Journal of Medicinal Chemistry|January 18, 2012
Diverse heterocyclic scaffolds as allosteric inhibitors of AKTJason G Kettle, Simon Brown, Claire Crafter, et al.Bioorganic & Medicinal Chemistry Letters|December 29, 2005
Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocketPeter Ballard, Robert H Bradbury, Craig S Harris, et al.Journal of the American Chemical Society|May 16, 2020
Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase InhibitorsKirsten McAulay, Emily A Hoyt, Morgan Thomas, et al.SLAS Discovery : Advancing Life Sciences R & D|November 29, 2024
High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRASMohamed Ismail, Gareth Davies, Graham Sproat, et al.Pageof 8