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Journal of Medicinal Chemistry|December 16, 2022
Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for OncologyFrederick W Goldberg, Jason G Kettle, Gillian M Lamont, et al.
Bioorganic & Medicinal Chemistry|December 18, 2021
Identification and optimization of a novel series of selective PIP5K inhibitorsDavid M Andrews, Sharon Cartic, Sabina Cosulich, et al.
Journal of Medicinal Chemistry|September 22, 2023
Discovery of the Potent and Selective Inhaled Janus Kinase 1 Inhibitor AZD4604 and Its Preclinical CharacterizationMagnus Nilsson, Kristina Berggren, Susanne Berglund, et al.
Journal of Medicinal Chemistry|February 17, 2016
Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell SurvivalJason G Kettle, Husam Alwan, Michal Bista, et al.
Bioorganic & Medicinal Chemistry Letters|September 18, 2007
Neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinasePeter Ballard, Bernard C Barlaam, Robert H Bradbury, et al.
Bioorganic & Medicinal Chemistry Letters|December 7, 2007
A new series of neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinaseBernard Barlaam, Peter Ballard, Robert H Bradbury, et al.
Journal of Medicinal Chemistry|February 20, 2015
Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activationJon J G Winter, Malcolm Anderson, Kevin Blades, et al.
Molecular Cancer Therapeutics|August 5, 2022
AZD4625 is a Potent and Selective Inhibitor of KRASG12CAtanu Chakraborty, Lyndsey Hanson, David Robinson, et al.
ACS Medicinal Chemistry Letters|October 15, 2025
Focused Structure-Based Virtual Screening Identifies Novel Inhibitors of SOS1Silvia Bonomo, Floriane Gibault, Sharan K Bagal, et al.
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