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Journal of Medicinal Chemistry|April 26, 2022
Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS<sup>G12C</sup>Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.Journal of Medicinal Chemistry|January 27, 2025
Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion MutationsWilliam McCoull, Clare Thomson, Erin Braybrooke, et al.Journal of Medicinal Chemistry|July 3, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS PenetrationJason G Kettle, Sharan K Bagal, Derek Barratt, et al.Journal of Medicinal Chemistry|February 10, 2025
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 InhibitorJason D Shields, David Baker, Amber Y S Balazs, et al.Pageof 8