Search research articles
Contact Us
Filters
Showing results (131-140 of 144) with videos related to
Page
of 15
Sort By:
Journal of Medicinal Chemistry
|
April 22, 2010
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521)
Scott H Watterson, Zili Xiao, Dharmpal S Dodd, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical Trials
T G Murali Dhar, Hai-Yun Xiao, Jenny Xie, et al.
Journal of Medicinal Chemistry
|
October 22, 2024
Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase
Jennifer X Qiao, David Williams, Patrice Gill, et al.
Medchemcomm
|
August 16, 2018
Identification of potent tricyclic prodrug S1P<sub>1</sub> receptor modulators
David Marcoux, Hai-Yun Xiao, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
December 2, 2020
Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches
Hai-Yun Xiao, Ning Li, James J-W Duan, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2017
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Hua Gong, David S Weinstein, Zhonghui Lu, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P<sub>1</sub> Receptor Modulator
Michael G Yang, Zili Xiao, T G Murali Dhar, et al.
ACS Medicinal Chemistry Letters
|
May 31, 2021
Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis
Qingjie Liu, Hai-Yun Xiao, Douglas G Batt, et al.
Journal of Medicinal Chemistry
|
February 21, 2019
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Modulator Advanced into Clinical Trials
John L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Page
of 15
Search research articles
Search
Showing results (131-140 of 144) with videos related to
Sort By:
Page
of 15
Journal of Medicinal Chemistry
|
April 22, 2010
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521)
Scott H Watterson, Zili Xiao, Dharmpal S Dodd, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical Trials
T G Murali Dhar, Hai-Yun Xiao, Jenny Xie, et al.
Journal of Medicinal Chemistry
|
October 22, 2024
Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase
Jennifer X Qiao, David Williams, Patrice Gill, et al.
Medchemcomm
|
August 16, 2018
Identification of potent tricyclic prodrug S1P<sub>1</sub> receptor modulators
David Marcoux, Hai-Yun Xiao, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
December 2, 2020
Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches
Hai-Yun Xiao, Ning Li, James J-W Duan, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2017
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Hua Gong, David S Weinstein, Zhonghui Lu, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P<sub>1</sub> Receptor Modulator
Michael G Yang, Zili Xiao, T G Murali Dhar, et al.
ACS Medicinal Chemistry Letters
|
May 31, 2021
Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis
Qingjie Liu, Hai-Yun Xiao, Douglas G Batt, et al.
Journal of Medicinal Chemistry
|
February 21, 2019
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Modulator Advanced into Clinical Trials
John L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Page
of 15