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G Salituro

Showing results (31-40 of 47) with videos related to

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Journal of Medicinal Chemistry|July 5, 2022
SAGE-718: A First-in-Class <i>N</i>-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive ImpairmentMatthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, et al.
Journal of Medicinal Chemistry|August 8, 2019
Neuroactive Steroid <i>N</i>-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological ActivityDaniel S La, Francesco G Salituro, Gabriel Martinez Botella, et al.
Journal of Medicinal Chemistry|March 24, 2015
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Science (New York, N.Y.)|May 13, 1999
Discovery of a small molecule insulin mimetic with antidiabetic activity in miceB Zhang, G Salituro, D Szalkowski, et al.
Journal of Medicinal Chemistry|July 29, 2017
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)<sub>A</sub> ReceptorGabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Neuropharmacology|September 25, 2020
Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA<sub>A</sub> receptor positive allosteric modulatorAlison L Althaus, Michael A Ackley, Gabriel M Belfort, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in VivoJaneta Popovici-Muller, Jeffrey O Saunders, Francesco G Salituro, et al.
Bioorganic & Medicinal Chemistry Letters|October 28, 2009
2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2Mark W Ledeboer, Albert C Pierce, John P Duffy, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
The Discovery of VX-745: A Novel and Selective p38α Kinase InhibitorJohn P Duffy, Edmund M Harrington, Francesco G Salituro, et al.
Journal of Medicinal Chemistry|December 18, 2009
Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindoleTiansheng Wang, John P Duffy, Jian Wang, et al.
Pageof 5

Showing results (31-40 of 47) with videos related to

Sort By:
Pageof 5
Journal of Medicinal Chemistry|July 5, 2022
SAGE-718: A First-in-Class <i>N</i>-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive ImpairmentMatthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, et al.
Journal of Medicinal Chemistry|August 8, 2019
Neuroactive Steroid <i>N</i>-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological ActivityDaniel S La, Francesco G Salituro, Gabriel Martinez Botella, et al.
Journal of Medicinal Chemistry|March 24, 2015
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Science (New York, N.Y.)|May 13, 1999
Discovery of a small molecule insulin mimetic with antidiabetic activity in miceB Zhang, G Salituro, D Szalkowski, et al.
Journal of Medicinal Chemistry|July 29, 2017
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)<sub>A</sub> ReceptorGabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Neuropharmacology|September 25, 2020
Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA<sub>A</sub> receptor positive allosteric modulatorAlison L Althaus, Michael A Ackley, Gabriel M Belfort, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in VivoJaneta Popovici-Muller, Jeffrey O Saunders, Francesco G Salituro, et al.
Bioorganic & Medicinal Chemistry Letters|October 28, 2009
2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2Mark W Ledeboer, Albert C Pierce, John P Duffy, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
The Discovery of VX-745: A Novel and Selective p38α Kinase InhibitorJohn P Duffy, Edmund M Harrington, Francesco G Salituro, et al.
Journal of Medicinal Chemistry|December 18, 2009
Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindoleTiansheng Wang, John P Duffy, Jian Wang, et al.
Pageof 5