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Journal of Chemical Theory and Computation
|
July 22, 2022
Asynchronous Reciprocal Coupling of Martini 2.2 Coarse-Grained and CHARMM36 All-Atom Simulations in an Automated Multiscale Framework
Cesar A López, Xiaohua Zhang, Fikret Aydin, et al.
Biophysical Journal
|
July 2, 2022
Exploring CRD mobility during RAS/RAF engagement at the membrane
Kien Nguyen, Cesar A López, Chris Neale, et al.
Biorxiv : the Preprint Server for Biology
|
September 2, 2025
An In Vitro BRAF Activation Assay Elucidates Molecular Mechanisms Driving Disassembly of the Autoinhibited BRAF State
Daniel A Ritt, David E Durrant, Matthew R Drew, et al.
Biorxiv : the Preprint Server for Biology
|
November 1, 2024
Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity
Jason J Kwon, Julien Dilly, Shengwu Liu, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
September 15, 2025
An in vitro BRAF activation assay elucidates molecular mechanisms driving disassembly of the autoinhibited BRAF state
Daniel A Ritt, David E Durrant, Matthew R Drew, et al.
Journal of Chemical Theory and Computation
|
April 19, 2023
Machine Learning-Driven Multiscale Modeling: Bridging the Scales with a Next-Generation Simulation Infrastructure
Helgi I Ingólfsson, Harsh Bhatia, Fikret Aydin, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
May 9, 2025
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
Anna E Maciag, Yue Yang, Alok K Sharma, et al.
Cancer Discovery
|
March 6, 2026
Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan, et al.
The Journal of Biological Chemistry
|
February 6, 2026
KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamics
Konstantia Georgouli, Jeremy O B Tempkin, Liam G Stanton, et al.
Cancer Discovery
|
December 6, 2024
Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
Anna E Maciag, James P Stice, Bin Wang, et al.
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Search research articles
Search
Showing results (251-260 of 266) with videos related to
Sort By:
Page
of 27
Journal of Chemical Theory and Computation
|
July 22, 2022
Asynchronous Reciprocal Coupling of Martini 2.2 Coarse-Grained and CHARMM36 All-Atom Simulations in an Automated Multiscale Framework
Cesar A López, Xiaohua Zhang, Fikret Aydin, et al.
Biophysical Journal
|
July 2, 2022
Exploring CRD mobility during RAS/RAF engagement at the membrane
Kien Nguyen, Cesar A López, Chris Neale, et al.
Biorxiv : the Preprint Server for Biology
|
September 2, 2025
An In Vitro BRAF Activation Assay Elucidates Molecular Mechanisms Driving Disassembly of the Autoinhibited BRAF State
Daniel A Ritt, David E Durrant, Matthew R Drew, et al.
Biorxiv : the Preprint Server for Biology
|
November 1, 2024
Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity
Jason J Kwon, Julien Dilly, Shengwu Liu, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
September 15, 2025
An in vitro BRAF activation assay elucidates molecular mechanisms driving disassembly of the autoinhibited BRAF state
Daniel A Ritt, David E Durrant, Matthew R Drew, et al.
Journal of Chemical Theory and Computation
|
April 19, 2023
Machine Learning-Driven Multiscale Modeling: Bridging the Scales with a Next-Generation Simulation Infrastructure
Helgi I Ingólfsson, Harsh Bhatia, Fikret Aydin, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
May 9, 2025
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
Anna E Maciag, Yue Yang, Alok K Sharma, et al.
Cancer Discovery
|
March 6, 2026
Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan, et al.
The Journal of Biological Chemistry
|
February 6, 2026
KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamics
Konstantia Georgouli, Jeremy O B Tempkin, Liam G Stanton, et al.
Cancer Discovery
|
December 6, 2024
Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
Anna E Maciag, James P Stice, Bin Wang, et al.
Page
of 27