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Bioorganic & Medicinal Chemistry Letters
|
June 16, 2005
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
Kwai-Ming J Cheung, Thomas P Matthews, Karen James, et al.
Journal of Medicinal Chemistry
|
March 13, 2012
Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity
Paolo Innocenti, Kwai-Ming J Cheung, Savade Solanki, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 22, 2010
Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinases
Thomas P Matthews, Tatiana McHardy, Suki Klair, et al.
Molecular Cancer Therapeutics
|
January 8, 2010
The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106
Michael I Walton, Paul D Eve, Angela Hayes, et al.
Journal of Medicinal Chemistry
|
July 4, 2009
Identification of inhibitors of checkpoint kinase 1 through template screening
Thomas P Matthews, Suki Klair, Samantha Burns, et al.
Plos One
|
January 19, 2012
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling
Simon R Stockwell, Georgina Platt, S Elaine Barrie, et al.
Journal of Medicinal Chemistry
|
October 13, 2010
Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization
Daniel K Whelligan, Savade Solanki, Dawn Taylor, et al.
Journal of Medicinal Chemistry
|
December 29, 2010
Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2
John J Caldwell, Emma J Welsh, Cornelis Matijssen, et al.
Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|
September 22, 2016
Percutaneous left atrial appendage occlusion using different technologies in the United Kingdom: A multicenter registry
Timothy R Betts, Milena Leo, Sandeep Panikker, et al.
Plos One
|
June 19, 2013
Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2
M Cris Silva-Santisteban, Isaac M Westwood, Kathy Boxall, et al.
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Search research articles
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Showing results (81-90 of 98) with videos related to
Sort By:
Page
of 10
Bioorganic & Medicinal Chemistry Letters
|
June 16, 2005
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
Kwai-Ming J Cheung, Thomas P Matthews, Karen James, et al.
Journal of Medicinal Chemistry
|
March 13, 2012
Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity
Paolo Innocenti, Kwai-Ming J Cheung, Savade Solanki, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 22, 2010
Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinases
Thomas P Matthews, Tatiana McHardy, Suki Klair, et al.
Molecular Cancer Therapeutics
|
January 8, 2010
The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106
Michael I Walton, Paul D Eve, Angela Hayes, et al.
Journal of Medicinal Chemistry
|
July 4, 2009
Identification of inhibitors of checkpoint kinase 1 through template screening
Thomas P Matthews, Suki Klair, Samantha Burns, et al.
Plos One
|
January 19, 2012
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling
Simon R Stockwell, Georgina Platt, S Elaine Barrie, et al.
Journal of Medicinal Chemistry
|
October 13, 2010
Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization
Daniel K Whelligan, Savade Solanki, Dawn Taylor, et al.
Journal of Medicinal Chemistry
|
December 29, 2010
Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2
John J Caldwell, Emma J Welsh, Cornelis Matijssen, et al.
Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|
September 22, 2016
Percutaneous left atrial appendage occlusion using different technologies in the United Kingdom: A multicenter registry
Timothy R Betts, Milena Leo, Sandeep Panikker, et al.
Plos One
|
June 19, 2013
Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2
M Cris Silva-Santisteban, Isaac M Westwood, Kathy Boxall, et al.
Page
of 10