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Pharmaceutical Statistics|January 12, 2018
Integrating dose estimation into a decision-making framework for model-based drug developmentJames Dunyak, Patrick Mitchell, Bengt Hamrén, et al.
Diabetes, Obesity & Metabolism|October 13, 2017
Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesisKaren M Hallow, Gabriel Helmlinger, Peter J Greasley, et al.
American Journal of Physiology. Renal Physiology|July 19, 2018
Evaluation of renal and cardiovascular protection mechanisms of SGLT2 inhibitors: model-based analysis of clinical dataK Melissa Hallow, Peter J Greasley, Gabriel Helmlinger, et al.
FEBS Letters|March 15, 2005
An integrated approach for inference and mechanistic modeling for advancing drug developmentSergej V Aksenov, Bruce Church, Anjali Dhiman, et al.
International Journal of Chronic Obstructive Pulmonary Disease|January 25, 2021
Longitudinal FEV<sub>1</sub> and Exacerbation Risk in COPD: Quantifying the Association Using Joint ModellingKirill Zhudenkov, Robert Palmér, Alexandra Jauhiainen, et al.
Progress in Biophysics and Molecular Biology|December 3, 2005
Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heartDean Bottino, R Christian Penland, Andrew stamps, et al.
Cellular and Molecular Gastroenterology and Hepatology|March 1, 2020
A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human BeingsVeronika Voronova, Victor Sokolov, Amani Al-Khaifi, et al.
Journal of Lipid Research|July 12, 2019
Comparative quantitative systems pharmacology modeling of anti-PCSK9 therapeutic modalities in hypercholesterolemiaVictor Sokolov, Gabriel Helmlinger, Catarina Nilsson, et al.
Journal for Immunotherapy of Cancer|March 1, 2018
Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems modelYuri Kosinsky, Simon J Dovedi, Kirill Peskov, et al.
Oncoimmunology|September 16, 2020
Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysisBoris Shulgin, Yuri Kosinsky, Andrey Omelchenko, et al.
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