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Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|April 7, 2025
A Compound Screen Based on Isogenic hESC-Derived β Cell Reveals an Inhibitor Targeting ZnT8-Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress-Induced Cell DeathRui Hu, Qing Ma, Yunhui Kong, et al.
Science Advances|September 10, 2025
Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs of type 1 diabetes progressionRebecca Melton, Sara Jimenez, Weston Elison, et al.
Biorxiv : the Preprint Server for Biology|March 3, 2025
Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progressionRebecca Melton, Sara Jimenez, Weston Elison, et al.
Cell Genomics|February 13, 2023
Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokinesPaola Benaglio, Han Zhu, Mei-Lin Okino, et al.
Cell Reports. Medicine|April 23, 2025
CD47-blocking antibody confers metabolic benefits against obesityYajuan Su, Jingyu Sun, Xiaobo Li, et al.
Nature Genetics|May 25, 2023
Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetesGaowei Wang, Joshua Chiou, Chun Zeng, et al.
Biorxiv : the Preprint Server for Biology|January 30, 2023
Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetesGaowei Wang, Joshua Chiou, Chun Zeng, et al.
The Journal of Clinical Investigation|February 23, 2023
Nutrient regulation of the islet epigenome controls adaptive insulin secretionMatthew Wortham, Fenfen Liu, Austin R Harrington, et al.
The Journal of Clinical Investigation|September 9, 2025
Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesisThomas Mandel Clausen, Ryan J Weiss, Jacob R Tremblay, et al.
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