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Journal of Molecular Biology|July 5, 2011
Whole-molecule antibody engineering: generation of a high-affinity anti-IL-6 antibody with extended pharmacokineticsDonna K Finch, Matthew A Sleeman, Jacques Moisan, et al.Journal for Immunotherapy of Cancer|April 17, 2025
LILRB2 blockade facilitates macrophage repolarization and enhances T cell-mediated antitumor immunityDes C Jones, Lorraine Irving, Rebecca Dudley, et al.Journal of Molecular Biology|October 20, 2009
Structure of IL-17A in complex with a potent, fully human neutralizing antibodyStefan Gerhardt, W Mark Abbott, David Hargreaves, et al.Neurobiology of Disease|August 25, 2019
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivoDarren J Schofield, Lorraine Irving, Laura Calo, et al.Mucosal Immunology|December 11, 2024
IL-33 is associated with alveolar dysfunction in patients with viral lower respiratory tract diseaseIan C Scott, Natalie van Zuydam, Jennifer A Cann, et al.Journal for Immunotherapy of Cancer|August 4, 2025
An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine releaseMiguel Gaspar, Marina Natoli, Laure Castan, et al.Journal of Immunology (Baltimore, Md. : 1950)|November 25, 2016
A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn BindingJulie Douthwaite, Jacques Moisan, Cyril Privezentzev, et al.Journal of Molecular Biology|June 6, 2024
Robust Prediction of Relative Binding Energies for Protein-Protein Complex Mutations Using Free Energy Perturbation CalculationsJared M Sampson, Daniel A Cannon, Jianxin Duan, et al.Biorxiv : the Preprint Server for Biology|May 7, 2024
Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculationsJared M Sampson, Daniel A Cannon, Jianxin Duan, et al.Mabs|March 4, 2014
A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthmaE Suzanne Cohen, Claire L Dobson, Helena Käck, et al.Pageof 15