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Cancers
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June 12, 2026
Pan-RAS Inhibitors: Expanding Therapeutic Potential and Evading Resistance
Sindhu Ramesh, Junwei Wang, Chung-Hui Huang, et al.
Journal of Ovarian Research
|
November 3, 2022
Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer
Rebecca M Borneman, Elaine Gavin, Alla Musiyenko, et al.
Plos One
|
October 13, 2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics
W Joon Chung, Jennifer L Goeckeler-Fried, Viktoria Havasi, et al.
Oncotarget
|
October 21, 2017
Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling
Bing Zhu, Ashley Lindsey, Nan Li, et al.
Biorxiv : the Preprint Server for Biology
|
February 23, 2026
ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, et al.
The Journal of Urology
|
January 10, 2004
First International Conference on Chemoprevention of Prostate Cancer. Overview consensus statement
Ian M Thompson, Demetrius Albanes, Joseph W Basler, et al.
Biorxiv : the Preprint Server for Biology
|
October 17, 2024
ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, et al.
Molecular Cancer
|
March 14, 2025
ADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, et al.
Cancer Prevention Research (Philadelphia, Pa.)
|
September 29, 2021
Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin
Kevin J Lee, Wen-Chi L Chang, Xi Chen, et al.
Pharmacological Reviews
|
March 13, 2025
Cyclic nucleotide phosphodiesterases as drug targets
Michy P Kelly, Viacheslav O Nikolaev, Leila Gobejishvili, et al.
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Search research articles
Search
Showing results (101-110 of 112) with videos related to
Sort By:
Page
of 12
Cancers
|
June 12, 2026
Pan-RAS Inhibitors: Expanding Therapeutic Potential and Evading Resistance
Sindhu Ramesh, Junwei Wang, Chung-Hui Huang, et al.
Journal of Ovarian Research
|
November 3, 2022
Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer
Rebecca M Borneman, Elaine Gavin, Alla Musiyenko, et al.
Plos One
|
October 13, 2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics
W Joon Chung, Jennifer L Goeckeler-Fried, Viktoria Havasi, et al.
Oncotarget
|
October 21, 2017
Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling
Bing Zhu, Ashley Lindsey, Nan Li, et al.
Biorxiv : the Preprint Server for Biology
|
February 23, 2026
ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, et al.
The Journal of Urology
|
January 10, 2004
First International Conference on Chemoprevention of Prostate Cancer. Overview consensus statement
Ian M Thompson, Demetrius Albanes, Joseph W Basler, et al.
Biorxiv : the Preprint Server for Biology
|
October 17, 2024
ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, et al.
Molecular Cancer
|
March 14, 2025
ADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, et al.
Cancer Prevention Research (Philadelphia, Pa.)
|
September 29, 2021
Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin
Kevin J Lee, Wen-Chi L Chang, Xi Chen, et al.
Pharmacological Reviews
|
March 13, 2025
Cyclic nucleotide phosphodiesterases as drug targets
Michy P Kelly, Viacheslav O Nikolaev, Leila Gobejishvili, et al.
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of 12