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Gary Aspnes

Showing results (1-10 of 10) with videos related to

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ACS Combinatorial Science|November 13, 2015
Expedient Synthesis of N1-Substituted Triazole PeptidomimeticsSteven B Coffey, Gary Aspnes, Allyn T Londregan
Nucleic Acids Research|March 15, 2025
Engineering oxypurinol-responsive riboswitches based on bacterial xanthine aptamers for gene expression control in mammalian cell cultureVera Hedwig, Maike Spöring, Julia Ottlinger, et al.
ACS Chemical Biology|January 5, 2026
Small Molecule-Controlled Gene Expression: Design of Drug-like High-Affinity Modulators of a Custom-Made RiboswitchVera Hedwig, Maike Spöring, Gary Aspnes, et al.
Bioorganic & Medicinal Chemistry Letters|November 29, 2018
Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9Allyn T Londregan, Gary Aspnes, Chris Limberakis, et al.
Bioorganic & Medicinal Chemistry Letters|January 15, 2014
Identification of a novel conformationally constrained glucagon receptor antagonistEsther C Y Lee, Meihua Tu, Benjamin D Stevens, et al.
Journal of Medicinal Chemistry|January 7, 2016
Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) FamilyKim Huard, James R Gosset, Justin I Montgomery, et al.
Scientific Reports|December 2, 2015
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)Kim Huard, Janice Brown, Jessica C Jones, et al.
Nature Communications|March 2, 2025
Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cellsWenyang Li, Robert P Sparks, Cheng Sun, et al.
Journal of Medicinal Chemistry|September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Journal of Medicinal Chemistry|December 27, 2011
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitusJeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, et al.
Pageof 1

Showing results (1-10 of 10) with videos related to

Sort By:
Pageof 1
ACS Combinatorial Science|November 13, 2015
Expedient Synthesis of N1-Substituted Triazole PeptidomimeticsSteven B Coffey, Gary Aspnes, Allyn T Londregan
Nucleic Acids Research|March 15, 2025
Engineering oxypurinol-responsive riboswitches based on bacterial xanthine aptamers for gene expression control in mammalian cell cultureVera Hedwig, Maike Spöring, Julia Ottlinger, et al.
ACS Chemical Biology|January 5, 2026
Small Molecule-Controlled Gene Expression: Design of Drug-like High-Affinity Modulators of a Custom-Made RiboswitchVera Hedwig, Maike Spöring, Gary Aspnes, et al.
Bioorganic & Medicinal Chemistry Letters|November 29, 2018
Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9Allyn T Londregan, Gary Aspnes, Chris Limberakis, et al.
Bioorganic & Medicinal Chemistry Letters|January 15, 2014
Identification of a novel conformationally constrained glucagon receptor antagonistEsther C Y Lee, Meihua Tu, Benjamin D Stevens, et al.
Journal of Medicinal Chemistry|January 7, 2016
Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) FamilyKim Huard, James R Gosset, Justin I Montgomery, et al.
Scientific Reports|December 2, 2015
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)Kim Huard, Janice Brown, Jessica C Jones, et al.
Nature Communications|March 2, 2025
Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cellsWenyang Li, Robert P Sparks, Cheng Sun, et al.
Journal of Medicinal Chemistry|September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Journal of Medicinal Chemistry|December 27, 2011
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitusJeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, et al.
Pageof 1