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Cancer Research|October 14, 2010
Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged miceRaleigh D Kladney, Robert D Cardiff, David J Kwiatkowski, et al.
Molecular and Cellular Biology|September 21, 2002
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycinChristine C Hudson, Mei Liu, Gary G Chiang, et al.
Bioorganic & Medicinal Chemistry|September 11, 2004
Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffoldZachary A Knight, Gary G Chiang, Peter J Alaimo, et al.
Organic & Biomolecular Chemistry|July 1, 2004
Synthesis and biological evaluation of synthetic viridins derived from C(20)-heteroalkylation of the steroidal PI-3-kinase inhibitor wortmanninPeter Wipf, Daniel J Minion, Robert J Halter, et al.
The Journal of Biological Chemistry|October 15, 2011
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effectDavid A Scott, Adam D Richardson, Fabian V Filipp, et al.
EMBO Reports|June 27, 2009
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligaseSamiksha Katiyar, Enbo Liu, Christine A Knutzen, et al.
Cell Reports|June 30, 2021
Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatomeDuygu Kuzuoglu-Ozturk, Zhiqiang Hu, Martina Rama, et al.
JCI Insight|May 25, 2021
mRNA translation is a therapeutic vulnerability necessary for bladder epithelial transformationSujata Jana, Rucha Deo, Rowan P Hough, et al.
Pigment Cell & Melanoma Research|May 20, 2011
Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathwaysYongmei Feng, Elisa Barile, Surya K De, et al.
Cancer Research|April 15, 2010
Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesisZhi Hong Lu, Mark B Shvartsman, Andrew Y Lee, et al.
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