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Regulatory Toxicology and Pharmacology : RTP
|
August 22, 2020
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations
Gary Gintant, Emily Pfeiffer Kaushik, Tromondae Feaster, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
May 3, 2018
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study
Daniel Millard, Qianyu Dang, Hong Shi, et al.
Cell Reports
|
September 27, 2018
International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
Ksenia Blinova, Qianyu Dang, Daniel Millard, et al.
Journal of Medicinal Chemistry
|
October 29, 2015
Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders
Adrian D Hobson, Christopher M Harris, Elizabeth L van der Kam, et al.
Scientific Reports
|
July 16, 2020
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
James Kramer, Herbert M Himmel, Anders Lindqvist, et al.
Scientific Reports
|
March 30, 2020
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
James Kramer, Herbert M Himmel, Anders Lindqvist, et al.
Journal of Biomolecular Screening
|
July 15, 2015
A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm
Bernard Fermini, Jules C Hancox, Najah Abi-Gerges, et al.
Bioorganic & Medicinal Chemistry
|
April 18, 2022
Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Na<sub>v</sub>1.7/ Nav1.8 blockers for the treatment of pain
Meena V Patel, Hillary M Peltier, Mark A Matulenko, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 14, 2007
Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity
Andrew S Judd, Andrew J Souers, Dariusz Wodka, et al.
Journal of Medicinal Chemistry
|
December 8, 2006
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction
Meena V Patel, Teodozyj Kolasa, Kathleen Mortell, et al.
Page
of 4
Search research articles
Search
Showing results (31-40 of 40) with videos related to
Sort By:
Page
of 4
You have reached the last page of results.
This site can display upto 40 results.
Regulatory Toxicology and Pharmacology : RTP
|
August 22, 2020
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations
Gary Gintant, Emily Pfeiffer Kaushik, Tromondae Feaster, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
May 3, 2018
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study
Daniel Millard, Qianyu Dang, Hong Shi, et al.
Cell Reports
|
September 27, 2018
International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
Ksenia Blinova, Qianyu Dang, Daniel Millard, et al.
Journal of Medicinal Chemistry
|
October 29, 2015
Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders
Adrian D Hobson, Christopher M Harris, Elizabeth L van der Kam, et al.
Scientific Reports
|
July 16, 2020
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
James Kramer, Herbert M Himmel, Anders Lindqvist, et al.
Scientific Reports
|
March 30, 2020
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
James Kramer, Herbert M Himmel, Anders Lindqvist, et al.
Journal of Biomolecular Screening
|
July 15, 2015
A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm
Bernard Fermini, Jules C Hancox, Najah Abi-Gerges, et al.
Bioorganic & Medicinal Chemistry
|
April 18, 2022
Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Na<sub>v</sub>1.7/ Nav1.8 blockers for the treatment of pain
Meena V Patel, Hillary M Peltier, Mark A Matulenko, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 14, 2007
Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity
Andrew S Judd, Andrew J Souers, Dariusz Wodka, et al.
Journal of Medicinal Chemistry
|
December 8, 2006
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction
Meena V Patel, Teodozyj Kolasa, Kathleen Mortell, et al.
Page
of 4