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The EMBO Journal|November 25, 2003
The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein trafficGregory K Scott, Feng Gu, Colin M Crump, et al.
Journal of Molecular Biology|June 30, 2012
Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3Stephanie L Dillon, Danielle M Williamson, Johannes Elferich, et al.
Biology Direct|November 8, 2021
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteinsMaria Sol Herrera-Cruz, Megan C Yap, Nasser Tahbaz, et al.
The Journal of Biological Chemistry|February 26, 2008
HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out miceKatelyn M Atkins, Laurel Thomas, Robert T Youker, et al.
Gastroenterology|January 13, 2006
Sustained phosphorylation of Bid is a marker for resistance to Fas-induced apoptosis during chronic liver diseasesArndt Vogel, Joseph E Aslan, Holger Willenbring, et al.
Oncotarget|January 10, 2018
Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancerSarah L Dombernowsky, Jeanette Schwarz, Jacob Samsøe-Petersen, et al.
Oncogene|January 29, 2020
The multifunctional protein PACS-1 is required for HDAC2- and HDAC3-dependent chromatin maturation and genomic stabilityChinnadurai Mani, Kaushlendra Tripathi, Shan Luan, et al.
Plos One|March 18, 2014
Cellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicityMaria Eugenia Guicciardi, Nathan W Werneburg, Steven F Bronk, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 13, 2002
Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasivenessJavier Mercapide, Ricardo Lopez De Cicco, Daniel E Bassi, et al.
The Journal of Biological Chemistry|May 31, 2012
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2)Nathan W Werneburg, Steve F Bronk, Maria Eugenia Guicciardi, et al.
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