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Nature Structural & Molecular Biology|April 3, 2007
Structural basis for autoinhibition of NotchWendy R Gordon, Didem Vardar-Ulu, Gavin Histen, et al.
Molecular and Cellular Biology|June 2, 2006
Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classesMichael J Malecki, Cheryll Sanchez-Irizarry, Jennifer L Mitchell, et al.
Plos One|October 25, 2011
Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivationJon C Aster, Nick Bodnar, Lanwei Xu, et al.
The Journal of Clinical Investigation|August 5, 2008
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemiaMark Y Chiang, Lanwei Xu, Olga Shestova, et al.
Molecular and Cellular Biology|August 2, 2006
Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1Mark Y Chiang, Mina L Xu, Gavin Histen, et al.
Plos One|August 25, 2009
Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2Wendy R Gordon, Didem Vardar-Ulu, Sarah L'Heureux, et al.
The Journal of Biological Chemistry|January 10, 2008
Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3Kang Li, Yucheng Li, Wenjuan Wu, et al.
Human Molecular Genetics|April 8, 2016
A mouse model of a human congenital disorder of glycosylation caused by loss of PMM2Barden Chan, Michelle Clasquin, Gromoslaw A Smolen, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 8, 2015
ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesisShengfang Jin, Jiang Chen, Lizao Chen, et al.
Blood|August 2, 2017
AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiencyCharles Kung, Jeff Hixon, Penelope A Kosinski, et al.
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