Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Gebhard Thoma

Showing results (11-20 of 28) with videos related to

Pageof 3
Sort By:
Chemistry (Weinheim an Der Bergstrasse, Germany)|October 19, 2005
Non-covalent polyvalent ligands by self-assembly of small glycodendrimers: a novel concept for the inhibition of polyvalent carbohydrate-protein interactions in vitro and in vivoGebhard Thoma, Markus B Streiff, Andreas G Katopodis, et al.
Bioorganic & Medicinal Chemistry Letters|September 1, 2015
Orally bioavailable Syk inhibitors with activity in a rat PK/PD modelGebhard Thoma, Siem Veenstra, Ross Strang, et al.
Bioorganic & Medicinal Chemistry Letters|September 29, 2009
Special ergolines are highly selective, potent antagonists of the chemokine receptor CXCR3: discovery, characterization and preliminary SAR of a promising leadGebhard Thoma, Rolf Baenteli, Ian Lewis, et al.
Chimia|December 9, 2010
In vivo neutralization of naturally existing antibodies against linear alpha(1,3)-galactosidic carbohydrate epitopes by multivalent antigen presentation: a solution for the first hurdle of pig-to-human xenotransplantationRudolf O Duthaler, Beat Ernst, Reto Fischer, et al.
Journal of Medicinal Chemistry|March 13, 2024
Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase InhibitorGebhard Thoma, Wolfgang Miltz, Honnappa Srinivas, et al.
European Journal of Immunology|January 31, 2003
Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivoTilo Biedermann, Christoph Schwärzler, Günther Lametschwandtner, et al.
Journal of Medicinal Chemistry|January 31, 2015
Discovery and profiling of a selective and efficacious Syk inhibitorGebhard Thoma, Alexander B Smith, Maurice J van Eis, et al.
Journal of Medicinal Chemistry|October 31, 2023
Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in BloodGebhard Thoma, Odile Decoret, Eric Vangrevelinghe, et al.
Journal of Medicinal Chemistry|January 19, 2023
Discovery and Characterization of the Topical Soft JAK Inhibitor CEE321 for Atopic DermatitisGebhard Thoma, Rudolf O Duthaler, Rudolf Waelchli, et al.
Clinical and Translational Science|February 26, 2024
LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trialChristian Loesche, Damien Picard, Benjamin Van Hoorick, et al.
Pageof 3

Showing results (11-20 of 28) with videos related to

Sort By:
Pageof 3
Chemistry (Weinheim an Der Bergstrasse, Germany)|October 19, 2005
Non-covalent polyvalent ligands by self-assembly of small glycodendrimers: a novel concept for the inhibition of polyvalent carbohydrate-protein interactions in vitro and in vivoGebhard Thoma, Markus B Streiff, Andreas G Katopodis, et al.
Bioorganic & Medicinal Chemistry Letters|September 1, 2015
Orally bioavailable Syk inhibitors with activity in a rat PK/PD modelGebhard Thoma, Siem Veenstra, Ross Strang, et al.
Bioorganic & Medicinal Chemistry Letters|September 29, 2009
Special ergolines are highly selective, potent antagonists of the chemokine receptor CXCR3: discovery, characterization and preliminary SAR of a promising leadGebhard Thoma, Rolf Baenteli, Ian Lewis, et al.
Chimia|December 9, 2010
In vivo neutralization of naturally existing antibodies against linear alpha(1,3)-galactosidic carbohydrate epitopes by multivalent antigen presentation: a solution for the first hurdle of pig-to-human xenotransplantationRudolf O Duthaler, Beat Ernst, Reto Fischer, et al.
Journal of Medicinal Chemistry|March 13, 2024
Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase InhibitorGebhard Thoma, Wolfgang Miltz, Honnappa Srinivas, et al.
European Journal of Immunology|January 31, 2003
Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivoTilo Biedermann, Christoph Schwärzler, Günther Lametschwandtner, et al.
Journal of Medicinal Chemistry|January 31, 2015
Discovery and profiling of a selective and efficacious Syk inhibitorGebhard Thoma, Alexander B Smith, Maurice J van Eis, et al.
Journal of Medicinal Chemistry|October 31, 2023
Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in BloodGebhard Thoma, Odile Decoret, Eric Vangrevelinghe, et al.
Journal of Medicinal Chemistry|January 19, 2023
Discovery and Characterization of the Topical Soft JAK Inhibitor CEE321 for Atopic DermatitisGebhard Thoma, Rudolf O Duthaler, Rudolf Waelchli, et al.
Clinical and Translational Science|February 26, 2024
LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trialChristian Loesche, Damien Picard, Benjamin Van Hoorick, et al.
Pageof 3