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The Journal of Biological Chemistry|September 25, 2002
SHP-2 is a dual-specificity phosphatase involved in Stat1 dephosphorylation at both tyrosine and serine residues in nucleiTong R Wu, Y Kate Hong, Xu-Dong Wang, et al.Cell Reports|June 20, 2019
TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune DiseasesBi-Huei Yang, Ke Wang, Shuo Wan, et al.Proceedings of the National Academy of Sciences of the United States of America|October 14, 2015
Shp2 and Pten have antagonistic roles in myeloproliferation but cooperate to promote erythropoiesis in mammalsHelen He Zhu, Xiaolin Luo, Kaiqing Zhang, et al.Journal of Cellular Physiology|April 22, 2016
SHP-2 Phosphatase Prevents Colonic Inflammation by Controlling Secretory Cell Differentiation and Maintaining Host-Microbiota HomeostasisGeneviève Coulombe, Ariane Langlois, Giada De Palma, et al.Proceedings of the National Academy of Sciences of the United States of America|April 21, 2017
Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinaseHao Ran, Shuangbo Kong, Shuang Zhang, et al.The Journal of Biological Chemistry|June 18, 2020
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levelsWen Liu, Ye Yin, Meijing Wang, et al.Blood|July 21, 2005
Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemiaRongzhen Xu, Yingzi Yu, Shu Zheng, et al.Proceedings of the National Academy of Sciences of the United States of America|February 10, 2016
Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprintingXuanyi Ma, Xin Qu, Wei Zhu, et al.Hepatology (Baltimore, Md.)|August 3, 2011
Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in miceLiang Li, Lei Chen, Liang Hu, et al.Molecular Cancer Therapeutics|June 28, 2013
Cyclin G1 expands liver tumor-initiating cells by Sox2 induction via Akt/mTOR signalingWen Wen, Tao Han, Cheng Chen, et al.Pageof 15