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Research Square|November 21, 2023
Imaging-based chromatin and epigenetic age, ImAge, quantitates aging and rejuvenationMartin Alvarez-Kuglen, Delany Rodriguez, Haodong Qin, et al.Cell Metabolism|July 2, 2014
Cytoplasmic tyrosine phosphatase Shp2 coordinates hepatic regulation of bile acid and FGF15/19 signaling to repress bile acid synthesisShuangwei Li, Diane D F Hsu, Bing Li, et al.Hepatology (Baltimore, Md.)|July 8, 2011
Gankyrin-mediated dedifferentiation facilitates the tumorigenicity of rat hepatocytes and hepatoma cellsWen Sun, Jin Ding, Kun Wu, et al.Nature Communications|November 14, 2023
Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolutionMeng Liu, Mengjun Ji, Jianghong Cheng, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 25, 2012
Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosisXue Zhang, Yun Zhang, Bo Tao, et al.JCI Insight|June 9, 2016
Abnormal <i>PTPN11</i> enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammationKeisuke Maeshima, Stephanie M Stanford, Deepa Hammaker, et al.Nature Aging|August 29, 2024
ImAge quantitates aging and rejuvenationMartin Alvarez-Kuglen, Kenta Ninomiya, Haodong Qin, et al.Molecular and Cellular Biology|November 13, 2008
Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature deathFrederic Princen, Emilie Bard, Farah Sheikh, et al.Gastroenterology|March 6, 2012
p28(GANK) prevents degradation of Oct4 and promotes expansion of tumor-initiating cells in hepatocarcinogenesisYou-Wen Qian, Yao Chen, Wen Yang, et al.Journal of Hepatology|April 14, 2015
PTPN11/Shp2 overexpression enhances liver cancer progression and predicts poor prognosis of patientsTao Han, Dai-Min Xiang, Wen Sun, et al.Pageof 15