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Biomedical Sciences Instrumentation|June 3, 2026
INHIBITING THE INHIBITOR: WOULD TARGETING PAI-1 RESULT IN A LOW-DOSE, WELL-TOLERATED TREATMENT OF EMPYEMA?Andrey A Komissarov, Christian J De Vera, René A Girard, et al.
The Journal of Biological Chemistry|February 5, 2015
Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungsAmarnath S Marudamuthu, Shwetha K Shetty, Yashodhar P Bhandary, et al.
International Journal of Molecular Sciences|August 29, 2024
Intrapleural Fibrinolytic Interventions for Retained Hemothoraces in RabbitsChristian J De Vera, Jincy Jacob, Krishna Sarva, et al.
Clinical and Translational Medicine|June 20, 2018
Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activatorSatoshi Fukuda, Perenlei Enkhbaatar, Christina Nelson, et al.
JCI Insight|April 19, 2019
Phase 1 trial of intrapleural LTI-01; single chain urokinase in complicated parapneumonic effusions or empyemaLutz Beckert, Ben Brockway, Graham Simpson, et al.
Science Translational Medicine|December 13, 2019
Caveolin-1-derived peptide limits development of pulmonary fibrosisAmarnath Satheesh Marudamuthu, Yashodhar Prabhakar Bhandary, Liang Fan, et al.
Experimental Brain Research|November 18, 2019
Increased expression of plasminogen activator inhibitor-1 (PAI-1) is associated with depression and depressive phenotype in C57Bl/6J miceRené A Girard, Prashant S Chauhan, Torry A Tucker, et al.
Respiratory Research|June 18, 2026
The LTI-01-2001 phase 2a trial of intrapleural LTI-01 in patients with infected, non-draining pleural effusionsCarla R Lamb, Jason Akulian, Ali Musani, et al.
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