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The Journal of Organic Chemistry|May 22, 2025
The Development of Synthetic Routes Leading to Pharmaceuticals and the Key Intermediates Using Hydroxynitrile LyaseJoy Chakraborty, Genji Iwasaki, Yasuhisa AsanoACS Omega|January 27, 2025
Imine Synthesis by Engineered d-Amino Acid Oxidase from Porcine KidneyWiyada Khangkhachit, Seiya Shirai, Genji Iwasaki, et al.Bioorganic & Medicinal Chemistry Letters|June 4, 2015
Synthesis and biological evaluation of quinones derived from natural product komaroviquinone as anti-Trypanosoma cruzi agentsYutaka Suto, Junko Nakajima-Shimada, Noriyuki Yamagiwa, et al.Bioorganic & Medicinal Chemistry Letters|April 1, 2008
New chemotypes for cathepsin K inhibitorsNaoki Teno, Osamu Irie, Takahiro Miyake, et al.Bioorganic & Medicinal Chemistry Letters|September 9, 2017
Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myelomaYutaka Suto, Mariko Sato, Kota Fujimori, et al.Biochemical and Biophysical Research Communications|October 10, 2018
A novel derivative (GTN024) from a natural product, komaroviquinone, induced the apoptosis of high-risk myeloma cells via reactive oxygen production and ER stressMikio Okayama, Shotaro Kitabatake, Mariko Sato, et al.Cancer Medicine|February 24, 2023
GTN057, a komaroviquinone derivative, induced myeloma cells' death in vivo and inhibited c-MET tyrosine kinaseMikio Okayama, Kota Fujimori, Mariko Sato, et al.Journal of Medicinal Chemistry|August 19, 2008
Effect of cathepsin K inhibitors on bone resorptionNaoki Teno, Keiichi Masuya, Takeru Ehara, et al.Bioorganic & Medicinal Chemistry Letters|July 30, 2008
4-Amino-2-cyanopyrimidines: novel scaffold for nonpeptidic cathepsin S inhibitorsOsamu Irie, Fumiaki Yokokawa, Takeru Ehara, et al.Bioorganic & Medicinal Chemistry Letters|June 24, 2008
Discovery of selective and nonpeptidic cathepsin S inhibitorsOsamu Irie, Takeru Ehara, Atsuko Iwasaki, et al.Pageof 2