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Cellular Immunology|March 27, 2018
Liver induced transgene tolerance with AAV vectorsGeoffrey D Keeler, David M Markusic, Brad E Hoffman
Molecular Therapy : the Journal of the American Society of Gene Therapy|September 26, 2017
Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple SclerosisGeoffrey D Keeler, Sandeep Kumar, Brett Palaschak, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|November 30, 2019
Type I IFN Sensing by cDCs and CD4+ T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8+ T CellsJamie L Shirley, Geoffrey D Keeler, Alexandra Sherman, et al.
Cellular Immunology|January 20, 2024
Upregulation of CD8+ regulatory T cells following liver-directed AAV gene therapyCristina D Gaddie, Kevin G Senior, Christopher Chan, et al.
Molecular Therapy. Methods & Clinical Development|October 15, 2016
Potential for cellular stress response to hepatic factor VIII expression from AAV vectorIrene Zolotukhin, David M Markusic, Brett Palaschak, et al.
EMBO Molecular Medicine|October 10, 2013
Effective gene therapy for haemophilic mice with pathogenic factor IX antibodiesDavid M Markusic, Brad E Hoffman, George Q Perrin, et al.
Molecular Therapy. Nucleic Acids|April 11, 2020
Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome EditingHua Yang, Keyun Qing, Geoffrey D Keeler, et al.
Molecular Therapy. Methods & Clinical Development|January 26, 2023
Induction of antigen-specific tolerance by hepatic AAV immunotherapy regardless of T cell epitope usage or mouse strain backgroundGeoffrey D Keeler, Cristina D Gaddie, Addelynn S Sagadevan, et al.
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