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ACS Chemical Biology|January 4, 2022
Repurposing the Damage Repair Protein Methyl Guanine Methyl Transferase as a Ligand Inducible Fusion DegronGosia M Murawska, Caspar Vogel, Max Jan, et al.Nature Structural & Molecular Biology|May 28, 2013
Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdownJeremiah J Frye, Nicholas G Brown, Georg Petzold, et al.Nature Structural & Molecular Biology|September 26, 2012
APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complexKristina Uzunova, Billy T Dye, Hannelore Schutz, et al.Molecular Cell|January 25, 2020
PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 NetworkKurt M Reichermeier, Ronny Straube, Justin M Reitsma, et al.Nature Methods|August 4, 2015
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical spaceAshwin Chari, David Haselbach, Jan-Martin Kirves, et al.Nature Chemical Biology|August 5, 2020
Rational discovery of molecular glue degraders via scalable chemical profilingCristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, et al.Nature|April 1, 2016
Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosomeSimone Cavadini, Eric S Fischer, Richard D Bunker, et al.Molecular Cell|October 14, 2014
Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assemblyNicholas G Brown, Edmond R Watson, Florian Weissmann, et al.Nature Chemical Biology|September 7, 2023
Design principles for cyclin K molecular glue degradersZuzanna Kozicka, Dakota J Suchyta, Vivian Focht, et al.Nature|June 5, 2020
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin KMikołaj Słabicki, Zuzanna Kozicka, Georg Petzold, et al.Pageof 3