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Bioorganic & Medicinal Chemistry Letters|December 8, 2009
Pyridine containing M(1) positive allosteric modulators with reduced plasma protein bindingScott D Kuduk, Christina N Di Marco, Victoria Cofre, et al.Bioorganic & Medicinal Chemistry Letters|April 6, 2005
Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSPChristopher D Cox, Michael J Breslin, Brenda J Mariano, et al.Bioorganic & Medicinal Chemistry Letters|January 25, 2011
High concentration electrophysiology-based fragment screen: discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitorsScott E Wolkenberg, Zhijian Zhao, James J Mulhearn, et al.Bioorganic & Medicinal Chemistry Letters|May 16, 2008
Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft modelMark T Bilodeau, Adrienne E Balitza, Jacob M Hoffman, et al.Bioorganic & Medicinal Chemistry Letters|June 15, 2011
Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3)Scott D Kuduk, Ronald K Chang, Christina N Di Marco, et al.Bioorganic & Medicinal Chemistry Letters|January 31, 2009
Discovery of N-{[1-(propylsulfonyl)-4-pyridin-2-ylpiperidin-4-yl]methyl}benzamides as novel, selective and potent GlyT1 inhibitorsZhijian Zhao, William H Leister, Julie A O'Brien, et al.Journal of Medicinal Chemistry|June 21, 2011
Discovery of a selective allosteric M1 receptor modulator with suitable development properties based on a quinolizidinone carboxylic acid scaffoldScott D Kuduk, Ronald K Chang, Christina N Di Marco, et al.Bioorganic & Medicinal Chemistry Letters|September 11, 2004
Nonpeptide alpha V beta 3 antagonists. Part 10: In vitro and in vivo evaluation of a potent 7-methyl substituted tetrahydro-[1,8]naphthyridine derivativeMichael J Breslin, Mark E Duggan, Wasyl Halczenko, et al.Bioorganic & Medicinal Chemistry Letters|December 17, 2009
Parallel synthesis of N-biaryl quinolone carboxylic acids as selective M(1) positive allosteric modulatorsFeng V Yang, William D Shipe, Jaime L Bunda, et al.Bioorganic & Medicinal Chemistry|November 15, 2011
Discovery of selective glucocorticoid receptor modulator MK-5932Christopher J Bungard, George D Hartman, Jesse J Manikowski, et al.Pageof 12