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European Journal of Clinical Pharmacology|June 4, 2010
Lack of effect of dalcetrapib on QT interval in healthy subjects following multiple dosingMichael Derks, Markus Abt, Anne Mwangi, et al.
Clinical Pharmacology and Therapeutics|July 18, 2024
PBPK Modeling of Entrectinib and Its Active Metabolite to Derive Dose Adjustments in Pediatric Populations Co-Administered with CYP3A4 InhibitorsKenichi Umehara, Neil Parrott, Emilie Schindler, et al.
Plos One|May 30, 2020
Therapeutically-induced stable disease in oncology early clinical trialsFrancois Mercier, Georgina Meneses-Lorente, Paul Grimsey, et al.
Cancer Chemotherapy and Pharmacology|February 4, 2022
Efficacy and safety exposure-response analyses of entrectinib in patients with advanced or metastatic solid tumorsFrancois Mercier, Nassim Djebli, Mario González-Sales, et al.
Clinical Therapeutics|June 28, 2011
Effects of food intake on the pharmacokinetic properties of dalcetrapib: findings from three phase I, single-dose crossover studies in healthy volunteersMichael Derks, Hitoshi Kawamura, Markus Abt, et al.
Expert Opinion on Investigational Drugs|August 27, 2010
No clinically relevant drug-drug interactions when dalcetrapib is co-administered with atorvastatinMichael Derks, Markus Abt, Graeme Parr, et al.
Analytical Biochemistry|February 14, 2006
A quantitative high-throughput trapping assay as a measurement of potential for bioactivationGeorgina Meneses-Lorente, Melanie Zea Sakatis, Timothy Schulz-Utermoehl, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 10, 2006
Utility of long-term cultured human hepatocytes as an in vitro model for cytochrome p450 inductionGeorgina Meneses-Lorente, Christine Pattison, Claire Guyomard, et al.
Cancer Chemotherapy and Pharmacology|May 13, 2017
Accelerating drug development by efficiently using emerging PK/PD data from an adaptable entry-into-human trial: example of lumretuzumabGeorgina Meneses-Lorente, Christine McIntyre, Joy C Hsu, et al.
Clinical Pharmacokinetics|February 11, 2025
Clinical Exploration and Physiologically Based Modelling of the Impact of Hepatic Impairment on Entrectinib PharmacokineticsAgustos C Ozbey, Georgina Meneses-Lorente, Brian Simmons, et al.
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