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Science (New York, N.Y.)|June 17, 2017
Click chemistry enables preclinical evaluation of targeted epigenetic therapiesDean S Tyler, Johanna Vappiani, Tatiana Cañeque, et al.Journal of Medicinal Chemistry|January 16, 2016
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one DerivativesSusan M Westaway, Alex G S Preston, Michael D Barker, et al.Nature Chemical Biology|January 19, 2021
BET bromodomain inhibitors regulate keratinocyte plasticityGabi Schutzius, Christian Kolter, Sebastian Bergling, et al.Cell Stem Cell|April 5, 2024
NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivoKenji Namoto, Clara Baader, Vanessa Orsini, et al.Nature Structural & Molecular Biology|June 14, 2016
Functional interdependence of BRD4 and DOT1L in MLL leukemiaOmer Gilan, Enid Y N Lam, Isabelle Becher, et al.Science Translational Medicine|October 19, 2022
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stagesLauren B Arendse, James M Murithi, Tarrick Qahash, et al.Nature Communications|September 2, 2016
Identification of KasA as the cellular target of an anti-tubercular scaffoldKatherine A Abrahams, Chun-Wa Chung, Sonja Ghidelli-Disse, et al.Nature|July 27, 2018
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasisSusan Wyllie, Michael Thomas, Stephen Patterson, et al.Journal of Medicinal Chemistry|January 16, 2016
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate DerivativesSusan M Westaway, Alex G S Preston, Michael D Barker, et al.Nature Chemical Biology|January 27, 2015
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formationHuw D Lewis, John Liddle, Jim E Coote, et al.Pageof 13