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Science Translational Medicine|October 19, 2022
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stagesLauren B Arendse, James M Murithi, Tarrick Qahash, et al.Nature Communications|September 2, 2016
Identification of KasA as the cellular target of an anti-tubercular scaffoldKatherine A Abrahams, Chun-Wa Chung, Sonja Ghidelli-Disse, et al.Nature|July 27, 2018
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasisSusan Wyllie, Michael Thomas, Stephen Patterson, et al.Nature|January 24, 2002
Functional organization of the yeast proteome by systematic analysis of protein complexesAnne-Claude Gavin, Markus Bösche, Roland Krause, et al.Journal of Medicinal Chemistry|January 16, 2016
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate DerivativesSusan M Westaway, Alex G S Preston, Michael D Barker, et al.Nature Chemical Biology|January 27, 2015
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formationHuw D Lewis, John Liddle, Jim E Coote, et al.Journal of Medicinal Chemistry|November 18, 2017
Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification StudiesColin R Wilson, Richard K Gessner, Atica Moosa, et al.Nature Chemical Biology|October 6, 2015
New IDH1 mutant inhibitors for treatment of acute myeloid leukemiaUjunwa C Okoye-Okafor, Boris Bartholdy, Jessy Cartier, et al.Science (New York, N.Y.)|March 21, 2020
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammationOmer Gilan, Inmaculada Rioja, Kathy Knezevic, et al.Science Translational Medicine|May 4, 2022
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosisMarion Flipo, Rosangela Frita, Marilyne Bourotte, et al.Pageof 8