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Acta Crystallographica. Section D, Biological Crystallography|May 7, 2010
Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei BenthVerena Janiak, Maike Petersen, Matthias Zentgraf, et al.Journal of Molecular Biology|May 10, 2005
The crystal structure of Plasmodium falciparum glutamate dehydrogenase, a putative target for novel antimalarial drugsChristof Werner, Milton T Stubbs, R Luise Krauth-Siegel, et al.Journal of Medicinal Chemistry|March 20, 2008
Structure-guided design of C2-symmetric HIV-1 protease inhibitors based on a pyrrolidine scaffoldAndreas Blum, Jark Böttcher, Andreas Heine, et al.Chemmedchem|January 15, 2016
Boosting Affinity by Correct Ligand Preorganization for the S2 Pocket of Thrombin: A Study by Isothermal Titration Calorimetry, Molecular Dynamics, and High-Resolution Crystal StructuresEggert H Rühmann, Melinda Rupp, Michael Betz, et al.Journal of Medicinal Chemistry|October 22, 2019
Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge ShieldingAnna Sandner, Tobias Hüfner-Wulsdorf, Andreas Heine, et al.Chembiochem : a European Journal of Chemical Biology|October 3, 2003
Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug designRuth Brenk, Milton T Stubbs, Andreas Heine, et al.Chemmedchem|December 7, 2019
Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening StrategiesEngi Hassaan, Per-Olof Eriksson, Stefan Geschwindner, et al.Journal of Medicinal Chemistry|January 9, 2013
Development of new cyclic plasmin inhibitors with excellent potency and selectivitySebastian M Saupe, Stephanie Leubner, Michael Betz, et al.Chemmedchem|June 6, 2023
Mutational Studies of Aldose Reductase to Trace a Transient Pocket Opening and to Explain Ligand Affinity CliffsLea-Sophie Klee, Marina Gárdonyi, Tobias Hüfner, et al.ACS Chemical Biology|August 20, 2021
OFF-State-Specific Inhibition of the Proprotein Convertase FurinSven O Dahms, Tanja Haider, Gerhard Klebe, et al.Pageof 25