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Chemmedchem|October 8, 2020
Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding PosesBarbara Wienen-Schmidt, Matthias Oebbeke, Khang Ngo, et al.Journal of the American Chemical Society|July 12, 2017
How Nothing Boosts Affinity: Hydrophobic Ligand Binding to the Virtually Vacated S<sub>1</sub>' Pocket of ThermolysinStefan G Krimmer, Jonathan Cramer, Johannes Schiebel, et al.Journal of Molecular Biology|August 12, 2008
Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 proteaseJark Böttcher, Andreas Blum, Andreas Heine, et al.Journal of Enzyme Inhibition and Medicinal Chemistry|May 12, 2016
Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitorsAlexander Maiwald, Maya Hammami, Sebastian Wagner, et al.The Journal of Biological Chemistry|August 12, 2003
An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coliJeffrey D Kittendorf, Tanja Sgraja, Klaus Reuter, et al.Journal of Molecular Biology|February 17, 2010
Non-additivity of functional group contributions in protein-ligand binding: a comprehensive study by crystallography and isothermal titration calorimetryBernhard Baum, Laveena Muley, Michael Smolinski, et al.Chemmedchem|August 22, 2012
Beyond heparinization: design of highly potent thrombin inhibitors suitable for surface couplingTorsten Steinmetzer, Bernhard Baum, Adam Biela, et al.Biochimica Et Biophysica Acta|December 20, 2014
Thermodynamic signatures of fragment binding: Validation of direct versus displacement ITC titrationsEggert Rühmann, Michael Betz, Marie Fricke, et al.Biochemical and Biophysical Research Communications|November 7, 2006
Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomeraseClemens Grimm, Ralf Ficner, Tanja Sgraja, et al.Journal of Molecular Biology|June 13, 2009
Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombinBernhard Baum, Laveena Muley, Andreas Heine, et al.Pageof 25