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ACS Chemical Biology|March 29, 2013
Launching spiking ligands into a protein-protein interface: a promising strategy to destabilize and break interface formation in a tRNA modifying enzymeFlorian Immekus, Luzi Jakob Barandun, Michael Betz, et al.
Chemmedchem|April 16, 2010
Fragment-based lead discovery: screening and optimizing fragments for thermolysin inhibitionLisa Englert, Katrin Silber, Holger Steuber, et al.
Chemmedchem|October 26, 2011
Development of improved PPARβ/δ inhibitorsPhilipp M Toth, Simone Naruhn, Veronika F S Pape, et al.
Angewandte Chemie (International Ed. in English)|January 30, 2015
Tracing binding modes in hit-to-lead optimization: chameleon-like poses of aspartic protease inhibitorsMaren Kuhnert, Helene Köster, Ruben Bartholomäus, et al.
Biochemistry|June 5, 2018
Homodimer Architecture of QTRT2, the Noncatalytic Subunit of the Eukaryotic tRNA-Guanine TransglycosylaseChristina Behrens, Inna Biela, Stéphanie Petiot-Bécard, et al.
ACS Chemical Biology|March 14, 2017
Price for Opening the Transient Specificity Pocket in Human Aldose Reductase upon Ligand Binding: Structural, Thermodynamic, Kinetic, and Computational AnalysisChris Rechlin, Frithjof Scheer, Felix Terwesten, et al.
European Journal of Medicinal Chemistry|January 12, 2005
Non-thiol farnesyltransferase inhibitors: N-(4-aminoacylamino-3-benzoylphenyl)-3-[5-(4-nitrophenyl)-2 furyl]acrylic acid amides and their antimalarial activityKatja Kettler, Jochen Wiesner, Katrin Silber, et al.
Journal of Medicinal Chemistry|December 25, 2015
Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental StudiesRoberto Gaspari, Chris Rechlin, Andreas Heine, et al.
Chemmedchem|January 25, 2019
Diamondoid Amino Acid-Based Peptide Kinase A Inhibitor AnaloguesJanis Müller, Romina A Kirschner, Jan-Philipp Berndt, et al.
Angewandte Chemie (International Ed. in English)|August 13, 2021
Unraveling a Ligand-Induced Twist of a Homodimeric Enzyme by Pulsed Electron-Electron Double ResonanceDzung Nguyen, Dinar Abdullin, Caspar A Heubach, et al.
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