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Chemistry (Weinheim an Der Bergstrasse, Germany)|December 9, 2014
Replacement of water molecules in a phosphate binding site by furanoside-appended lin-benzoguanine ligands of tRNA-guanine transglycosylase (TGT)Luzi J Barandun, Frederik R Ehrmann, Daniel Zimmerli, et al.European Journal of Medicinal Chemistry|November 21, 2022
Pose, duplicate, then elaborate: Steps towards increased affinity for inhibitors targeting the specificity surface of the Pim-1 kinaseLukas Heyder, Phil M M Hochban, Corey Taylor, et al.Journal of Medicinal Chemistry|June 19, 2018
Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase BindingBarbara Wienen-Schmidt, Hendrik R A Jonker, Tobias Wulsdorf, et al.Chemmedchem|February 22, 2024
Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin InhibitorsRoman W Lange, Konstantin Bloch, Miriam Ruth Heindl, et al.Journal of Medicinal Chemistry|November 11, 2005
Benzophenone-based farnesyltransferase inhibitors with high activity against Trypanosoma cruziMónica I Esteva, Katja Kettler, Cristina Maidana, et al.Structure (London, England : 1993)|July 1, 2023
The C-terminus of Sudan ebolavirus VP40 contains a functionally important CX<sub>n</sub>C motif, a target for redox modificationsAnke-Dorothee Werner, Martin Schauflinger, Michael J Norris, et al.ACS Chemical Biology|March 31, 2016
Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case StudyJohannes Schiebel, Nedyalka Radeva, Stefan G Krimmer, et al.Journal of Medicinal Chemistry|July 28, 2016
Experimental Active-Site Mapping by Fragments: Hot Spots Remote from the Catalytic Center of EndothiapepsinNedyalka Radeva, Stefan G Krimmer, Martin Stieler, et al.European Journal of Medicinal Chemistry|June 3, 2018
Structure-based design and profiling of novel 17β-HSD14 inhibitorsFlorian Braun, Nicole Bertoletti, Gabriele Möller, et al.Acta Crystallographica. Section D, Biological Crystallography|March 7, 2014
Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug designAlexandra Cousido-Siah, Francesc X Ruiz, André Mitschler, et al.Pageof 25