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Methods in Molecular Biology (Clifton, N.J.)|July 24, 2014
Small molecules that inhibit Notch signalingGerdien E De Kloe, Bart De StrooperDrug Discovery Today|May 16, 2009
Transforming fragments into candidates: small becomes big in medicinal chemistryGerdien E de Kloe, David Bailey, Rob Leurs, et al.Biochemistry|August 13, 2010
Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding proteinMatthis Geitmann, Kim Retra, Gerdien E de Kloe, et al.Nature Communications|May 23, 2013
Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding proteinMariano Stornaiuolo, Gerdien E De Kloe, Prakash Rucktooa, et al.Journal of Medicinal Chemistry|June 4, 2010
Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identificationJeroen Kool, Gerdien E de Kloe, Ben Bruyneel, et al.Analytical and Bioanalytical Chemistry|September 28, 2010
Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assaysFerry Heus, Martin Giera, Gerdien E de Kloe, et al.Journal of Medicinal Chemistry|September 11, 2010
Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligandsGerdien E de Kloe, Kim Retra, Matthis Geitmann, et al.Drug Discovery Today|December 26, 2012
Small and colorful stones make beautiful mosaics: fragment-based chemogenomicsChris de Graaf, Henry F Vischer, Gerdien E de Kloe, et al.Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃AMark H P Verheij, Chris de Graaf, Gerdien E de Kloe, et al.Pageof 1