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European Journal of Pharmacology|September 25, 2010
Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transitRobert W Busby, Alexander P Bryant, Wilmin P Bartolini, et al.JCI Insight|October 5, 2018
Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunctionLuke Grundy, Andrea M Harrington, Joel Castro, et al.Life Sciences|March 24, 2010
Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tractAlexander P Bryant, Robert W Busby, Wilmin P Bartolini, et al.Bioorganic & Medicinal Chemistry Letters|March 14, 2009
Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonistsGhotas Evindar, Alexander L Satz, Sylvie G Bernier, et al.Pain|June 11, 2013
Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activationInmaculada Silos-Santiago, Gerhard Hannig, Helene Eutamene, et al.Gastroenterology|August 21, 2013
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphateJoel Castro, Andrea M Harrington, Patrick A Hughes, et al.Journal of Medicinal Chemistry|November 26, 2009
Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2Christopher C Arico-Muendel, Dennis R Benjamin, Teresa M Caiazzo, et al.Pageof 3