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Molecular Neurobiology|December 15, 2012
Mechanisms of granulin deficiency: lessons from cellular and animal modelsGernot Kleinberger, Anja Capell, Christian Haass, et al.
Biochemical Society Transactions|July 27, 2011
The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degenerationJonathan Janssens, Gernot Kleinberger, Hans Wils, et al.
EMBO Molecular Medicine|September 1, 2017
An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic functionKai Schlepckow, Gernot Kleinberger, Akio Fukumori, et al.
Journal of Neurochemistry|August 25, 2010
Increased caspase activation and decreased TDP-43 solubility in progranulin knockout cortical culturesGernot Kleinberger, Hans Wils, Peter Ponsaerts, et al.
Neurobiology of Aging|January 27, 2016
Reduced secretion and altered proteolytic processing caused by missense mutations in progranulinGernot Kleinberger, Anja Capell, Nathalie Brouwers, et al.
Molecular Neurobiology|March 12, 2013
Overexpression of ALS-associated p.M337V human TDP-43 in mice worsens disease features compared to wild-type human TDP-43 miceJonathan Janssens, Hans Wils, Gernot Kleinberger, et al.
EMBO Molecular Medicine|July 13, 2016
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearanceXianyuan Xiang, Georg Werner, Bernd Bohrmann, et al.
Neurobiology of Aging|December 3, 2014
Functional complementation in Drosophila to predict the pathogenicity of TARDBP variants: evidence for a loss-of-function mechanismLies Vanden Broeck, Gernot Kleinberger, Julien Chapuis, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 6, 2010
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degenerationHans Wils, Gernot Kleinberger, Jonathan Janssens, et al.
Science Translational Medicine|December 16, 2016
Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injuryMarc Suárez-Calvet, Miguel Ángel Araque Caballero, Gernot Kleinberger, et al.
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