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Molecular Neurodegeneration|January 12, 2019
Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathologyMarc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, et al.Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|September 29, 2018
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP MiceCarola Focke, Tanja Blume, Benedikt Zott, et al.Proceedings of the National Academy of Sciences of the United States of America|June 6, 2022
Signatures of glial activity can be detected in the CSF proteomeTimo Eninger, Stephan A Müller, Mehtap Bacioglu, et al.EMBO Molecular Medicine|May 25, 2019
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolismJulia K Götzl, Matthias Brendel, Georg Werner, et al.Acta Neuropathologica Communications|November 12, 2015
Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brainsJonathan Janssens, Stéphanie Philtjens, Gernot Kleinberger, et al.The Lancet. Neurology|March 19, 2022
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational studyEstrella Morenas-Rodríguez, Yan Li, Brigitte Nuscher, et al.EMBO Molecular Medicine|March 5, 2016
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markersMarc Suárez-Calvet, Gernot Kleinberger, Miguel Ángel Araque Caballero, et al.EMBO Molecular Medicine|March 11, 2020
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk regionKai Schlepckow, Kathryn M Monroe, Gernot Kleinberger, et al.Theranostics|September 15, 2021
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulationGloria Biechele, Tanja Blume, Maximilian Deussing, et al.Frontiers in Aging Neuroscience|April 18, 2022
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves CognitionTanja Blume, Maximilian Deussing, Gloria Biechele, et al.Pageof 5