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Plos One|May 26, 2022
Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease riskMuhammad Ali, Yun Ju Sung, Fengxian Wang, et al.EMBO Molecular Medicine|November 29, 2018
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive declineMarc Suárez-Calvet, Anja Capell, Miguel Ángel Araque Caballero, et al.The EMBO Journal|January 12, 2022
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiencyAnika Reifschneider, Sophie Robinson, Bettina van Lengerich, et al.Nature Neuroscience|January 9, 2019
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoESamira Parhizkar, Thomas Arzberger, Matthias Brendel, et al.Science Translational Medicine|July 4, 2014
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosisGernot Kleinberger, Yoshinori Yamanishi, Marc Suárez-Calvet, et al.Science Translational Medicine|August 16, 2019
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease riskYuetiva Deming, Fabia Filipello, Francesca Cignarella, et al.The Lancet. Neurology|December 14, 2011
A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification studyIlse Gijselinck, Tim Van Langenhove, Julie van der Zee, et al.Pageof 5