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Cancer Discovery
|
April 8, 2015
Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397
Catherine C Smith, Chao Zhang, Kimberly C Lin, et al.
Gynecologic Oncology
|
March 23, 2023
Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor
Blair McNamara, Justin Harold, Diego Manavella, et al.
JCI Insight
|
July 27, 2018
The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma
Orsi Giricz, Yongkai Mo, Kimberly B Dahlman, et al.
Nature
|
October 16, 2015
RAF inhibitors that evade paradoxical MAPK pathway activation
Chao Zhang, Wayne Spevak, Ying Zhang, et al.
JAMA Oncology
|
July 8, 2021
Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial
Andrew J Wagner, Paul L Severson, Anthony F Shields, et al.
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|
April 10, 2013
Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma
Kerstin Trunzer, Anna C Pavlick, Lynn Schuchter, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 1, 2009
Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent
Dean R Artis, Jack J Lin, Chao Zhang, et al.
Neuro-Oncology
|
July 5, 2022
MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus
Peter M K de Blank, Andrea M Gross, Srivandana Akshintala, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 22, 2008
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
James Tsai, John T Lee, Weiru Wang, et al.
Nature
|
September 9, 2010
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
Gideon Bollag, Peter Hirth, James Tsai, et al.
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Search research articles
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Showing results (71-80 of 84) with videos related to
Sort By:
Page
of 9
Cancer Discovery
|
April 8, 2015
Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397
Catherine C Smith, Chao Zhang, Kimberly C Lin, et al.
Gynecologic Oncology
|
March 23, 2023
Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor
Blair McNamara, Justin Harold, Diego Manavella, et al.
JCI Insight
|
July 27, 2018
The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma
Orsi Giricz, Yongkai Mo, Kimberly B Dahlman, et al.
Nature
|
October 16, 2015
RAF inhibitors that evade paradoxical MAPK pathway activation
Chao Zhang, Wayne Spevak, Ying Zhang, et al.
JAMA Oncology
|
July 8, 2021
Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial
Andrew J Wagner, Paul L Severson, Anthony F Shields, et al.
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|
April 10, 2013
Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma
Kerstin Trunzer, Anna C Pavlick, Lynn Schuchter, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 1, 2009
Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent
Dean R Artis, Jack J Lin, Chao Zhang, et al.
Neuro-Oncology
|
July 5, 2022
MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus
Peter M K de Blank, Andrea M Gross, Srivandana Akshintala, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 22, 2008
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
James Tsai, John T Lee, Weiru Wang, et al.
Nature
|
September 9, 2010
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
Gideon Bollag, Peter Hirth, James Tsai, et al.
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of 9