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The EMBO Journal
|
January 12, 2022
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency
Anika Reifschneider, Sophie Robinson, Bettina van Lengerich, et al.
Science Translational Medicine
|
June 5, 2024
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration
Marvin Reich, Matthew J Simon, Beate Polke, et al.
Biorxiv : the Preprint Server for Biology
|
February 26, 2024
Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia
Jennifer Hsiao-Nakamoto, Chi-Lu Chiu, Lawren VandeVrede, et al.
Neuron
|
January 7, 2020
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
Alicia A Nugent, Karin Lin, Bettina van Lengerich, et al.
Molecular Neurodegeneration
|
August 7, 2025
LRRK2 kinase activity regulates Parkinson's disease-relevant lipids at the lysosome
Michael T Maloney, Xiang Wang, Rajarshi Ghosh, et al.
Movement Disorders : Official Journal of the Movement Disorder Society
|
November 28, 2023
The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson's Disease in India
Shan V Andrews, Prashanth L Kukkle, Ramesh Menon, et al.
Cell Reports
|
January 17, 2026
Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice
G Travis Tabor, Alexandra Litvinchuk, Yun Chen, et al.
Science Translational Medicine
|
December 4, 2024
Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease
Lina Dinkel, Selina Hummel, Valerio Zenatti, et al.
Biorxiv : the Preprint Server for Biology
|
October 1, 2025
A Common PD-Risk <i>GBA1</i> Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial Dysfunction
Oliver B Davis, Jennifer E Kung, Sonnet S Davis, et al.
Nature Communications
|
January 24, 2026
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism
Astrid F Feiten, Kilian Dahm, Kai Schlepckow, et al.
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Showing results (101-110 of 119) with videos related to
Sort By:
Page
of 12
The EMBO Journal
|
January 12, 2022
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency
Anika Reifschneider, Sophie Robinson, Bettina van Lengerich, et al.
Science Translational Medicine
|
June 5, 2024
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration
Marvin Reich, Matthew J Simon, Beate Polke, et al.
Biorxiv : the Preprint Server for Biology
|
February 26, 2024
Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia
Jennifer Hsiao-Nakamoto, Chi-Lu Chiu, Lawren VandeVrede, et al.
Neuron
|
January 7, 2020
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
Alicia A Nugent, Karin Lin, Bettina van Lengerich, et al.
Molecular Neurodegeneration
|
August 7, 2025
LRRK2 kinase activity regulates Parkinson's disease-relevant lipids at the lysosome
Michael T Maloney, Xiang Wang, Rajarshi Ghosh, et al.
Movement Disorders : Official Journal of the Movement Disorder Society
|
November 28, 2023
The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson's Disease in India
Shan V Andrews, Prashanth L Kukkle, Ramesh Menon, et al.
Cell Reports
|
January 17, 2026
Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice
G Travis Tabor, Alexandra Litvinchuk, Yun Chen, et al.
Science Translational Medicine
|
December 4, 2024
Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease
Lina Dinkel, Selina Hummel, Valerio Zenatti, et al.
Biorxiv : the Preprint Server for Biology
|
October 1, 2025
A Common PD-Risk <i>GBA1</i> Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial Dysfunction
Oliver B Davis, Jennifer E Kung, Sonnet S Davis, et al.
Nature Communications
|
January 24, 2026
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism
Astrid F Feiten, Kilian Dahm, Kai Schlepckow, et al.
Page
of 12