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Expert Opinion on Drug Metabolism & Toxicology|October 6, 2023
The safety and toxicity profile of SPL84, an inhaled antisense oligonucleotide for treatment of cystic fibrosis patients with the 3849 +10kb C->T mutation, supports a Phase 1/2 clinical studyLital Friedman, Ofra-Barchad Avitzur, Efrat Ozeri Galai, et al.Molecular Pharmaceutics|December 30, 2015
In Vitro and in Vivo Characterization of MOD-4023, a Long-Acting Carboxy-Terminal Peptide (CTP)-Modified Human Growth HormoneOren Hershkovitz, Ahuva Bar-Ilan, Rachel Guy, et al.Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society|January 8, 2026
Intestinal organoids as a platform for functional evaluation of ASO-mediated splicing modulation in cystic fibrosisNoemie Stanleigh, Michal Irony-Tur Sinai, Yifat Oren, et al.Nucleic Acid Therapeutics|August 29, 2023
Delivery Characterization of SPL84 Inhaled Antisense Oligonucleotide Drug for 3849 + 10 kb C- > T Cystic Fibrosis PatientsEfrat Ozeri-Galai, Lital Friedman, Ofra Barchad-Avitzur, et al.The Journal of Clinical Endocrinology and Metabolism|March 22, 2017
Long-Acting C-Terminal Peptide-Modified hGH (MOD-4023): Results of a Safety and Dose-Finding Study in GHD ChildrenNataliya Zelinska, Violeta Iotova, Julia Skorodok, et al.Blood|September 20, 2008
Anti-inflammatory effects of an inflammatory chemokine: CCL2 inhibits lymphocyte homing by modulation of CCL21-triggered integrin-mediated adhesionsLiat Flaishon, Gili Hart, Einat Zelman, et al.Inflammatory Bowel Diseases|November 4, 2015
CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel DiseaseEinat Zelman-Toister, Eszter Bakos, Sivan Cohen, et al.Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society|June 25, 2026
SPL84 and trikafta® exhibit comparable and additive effects in patient-derived HBE cells carrying the 3849+10kb C→T/F508del CFTR variantsYi Cheng, Yifat S Oren, Jan Harrington, et al.European Journal of Endocrinology|December 10, 2016
MOD-4023, a long-acting carboxy-terminal peptide-modified human growth hormone: results of a Phase 2 study in growth hormone-deficient adultsChristian J Strasburger, Peter Vanuga, Juraj Payer, et al.Pageof 2