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Neurobiology of Disease|October 9, 2007
Increased metabolism in the R6/2 mouse model of Huntington's diseaseJorien M M van der Burg, Karl Bacos, Nigel I Wood, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 12, 2005
A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivoXiaoqian Zhang, Donna L Smith, Anatoli B Meriin, et al.
Disease Models & Mechanisms|May 26, 2026
Molecular features of a Huntington's disease knock-in minipigAnastasiia Kolesnikova, Kirupa Sathasivam, Solaleh Khoramian Tusi, et al.
Plos One|March 27, 2019
Meso scale discovery-based assays for the detection of aggregated huntingtinWolfgang Reindl, Barbara Baldo, Jana Schulz, et al.
Somatic Cell and Molecular Genetics|January 1, 1994
Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeatChristine M Ambrose, Mabel P Duyao, Glenn Barnes, et al.
Brain : a Journal of Neurology|January 25, 2014
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulationUlrike Träger, Ralph Andre, Nayana Lahiri, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 10, 2010
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesisRuth Luthi-Carter, David M Taylor, Judit Pallos, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 23, 2013
Targeting H3K4 trimethylation in Huntington diseaseMalini Vashishtha, Christopher W Ng, Ferah Yildirim, et al.
Brain : a Journal of Neurology|February 2, 2026
The HTT1a protein initiates HTT aggregation in a knock-in mouse model of Huntington's diseaseAikaterini Smaragdi Papadopoulou, Christian Landles, Edward J Smith, et al.
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