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The Journal of Biological Chemistry|November 8, 2018
Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assemblyMeng Lu, Luca Banetta, Laurence J Young, et al.
Plos One|August 21, 2014
Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD miceSilvia Corrochano, Maurizio Renna, Georgina Osborne, et al.
Nature|August 10, 2007
Global changes to the ubiquitin system in Huntington's diseaseEric J Bennett, Thomas A Shaler, Ben Woodman, et al.
Brain Communications|December 23, 2024
Mutant huntingtin protein decreases with CAG repeat expansion: implications for therapeutics and bioassaysChristian Landles, Georgina F Osborne, Jemima Phillips, et al.
The Journal of Clinical Investigation|July 26, 2011
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington diseaseJohn Labbadia, Helen Cunliffe, Andreas Weiss, et al.
Human Molecular Genetics|April 15, 2006
Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's diseaseMaria Björkqvist, Asa Petersén, Karl Bacos, et al.
Combinatorial Chemistry & High Throughput Screening|October 21, 2010
PLUXter: rapid discovery of metal-organic framework structures using PCA and HCA of high throughput synchrotron powder diffraction dataDeborah Lau, David G Hay, Matthew R Hill, et al.
Plos One|December 27, 2022
Reduction in PA28αβ activation in HD mouse brain correlates to increased mHTT aggregation in cell modelsKarlijne W Geijtenbeek, Jolien Janzen, Aleksandra E Bury, et al.
Brain Communications|February 19, 2021
Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platformsChristian Landles, Rebecca E Milton, Alexandre Jean, et al.
Brain : a Journal of Neurology|August 18, 2024
Exon 1-targeting miRNA reduces the pathogenic exon 1 HTT protein in Huntington's disease modelsMarina Sogorb-Gonzalez, Christian Landles, Nicholas S Caron, et al.
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