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Science Translational Medicine
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March 18, 2026
Lowering the <i>HTT1a</i> transcript as an effective therapy for Huntington's disease in a knockin mouse model
Aikaterini Smaragdi Papadopoulou, Julia Alterman, Christian Landles, et al.
Plos Biology
|
December 5, 2013
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration
Michal Mielcarek, Christian Landles, Andreas Weiss, et al.
Neuron
|
February 3, 2022
Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice
Xiaofeng Gu, Jeffrey Richman, Peter Langfelder, et al.
The Journal of Experimental Medicine
|
July 16, 2008
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
Maria Björkqvist, Edward J Wild, Jenny Thiele, et al.
Glia
|
September 13, 2016
Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific
Anne H P Jansen, Maurik van Hal, Ilse C Op den Kelder, et al.
Genome Research
|
April 25, 2015
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity
Martin Stroedicke, Yacine Bounab, Nadine Strempel, et al.
Molecular Cell
|
September 8, 2018
mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease
Anne Ast, Alexander Buntru, Franziska Schindler, et al.
Biorxiv : the Preprint Server for Biology
|
July 16, 2025
Blocking somatic repeat expansion and lowering huntingtin via RNA interference synergize to prevent Huntington's disease pathogenesis in mice
Jillian Belgrad, Ashley Summers, Christian Landles, et al.
Molecular Cell
|
May 7, 2016
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
Vaishali Kakkar, Cecilia Månsson, Eduardo P de Mattos, et al.
Cell Reports
|
July 23, 2013
SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation
Jacqueline Gire O'Rourke, Jaclyn R Gareau, Joseph Ochaba, et al.
Page
of 15
Search research articles
Search
Showing results (131-140 of 142) with videos related to
Sort By:
Page
of 15
Science Translational Medicine
|
March 18, 2026
Lowering the <i>HTT1a</i> transcript as an effective therapy for Huntington's disease in a knockin mouse model
Aikaterini Smaragdi Papadopoulou, Julia Alterman, Christian Landles, et al.
Plos Biology
|
December 5, 2013
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration
Michal Mielcarek, Christian Landles, Andreas Weiss, et al.
Neuron
|
February 3, 2022
Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice
Xiaofeng Gu, Jeffrey Richman, Peter Langfelder, et al.
The Journal of Experimental Medicine
|
July 16, 2008
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
Maria Björkqvist, Edward J Wild, Jenny Thiele, et al.
Glia
|
September 13, 2016
Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific
Anne H P Jansen, Maurik van Hal, Ilse C Op den Kelder, et al.
Genome Research
|
April 25, 2015
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity
Martin Stroedicke, Yacine Bounab, Nadine Strempel, et al.
Molecular Cell
|
September 8, 2018
mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease
Anne Ast, Alexander Buntru, Franziska Schindler, et al.
Biorxiv : the Preprint Server for Biology
|
July 16, 2025
Blocking somatic repeat expansion and lowering huntingtin via RNA interference synergize to prevent Huntington's disease pathogenesis in mice
Jillian Belgrad, Ashley Summers, Christian Landles, et al.
Molecular Cell
|
May 7, 2016
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
Vaishali Kakkar, Cecilia Månsson, Eduardo P de Mattos, et al.
Cell Reports
|
July 23, 2013
SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation
Jacqueline Gire O'Rourke, Jaclyn R Gareau, Joseph Ochaba, et al.
Page
of 15