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Scientific Reports|November 19, 2020
Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screenLina Schukur, Tamara Zimmermann, Ole Niewoehner, et al.
Nature Communications|August 22, 2019
PAX8 activates metabolic genes via enhancer elements in Renal Cell CarcinomaMelusine Bleu, Swann Gaulis, Rui Lopes, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 22, 2026
Targeting CRTC2 reverses STK11 mutant NSCLC tumor resistance to immunotherapyDimitri Robay, Ole Ackermann, Laurent Laborde, et al.
Cancer Cell|August 5, 2014
The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formationAnnie M Tremblay, Edoardo Missiaglia, Giorgio G Galli, et al.
Nature Communications|July 3, 2023
Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screensInês A M Barbosa, Rajaraman Gopalakrishnan, Samuele Mercan, et al.
Nature Cell Biology|July 19, 2016
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growthAndrew G Cox, Katie L Hwang, Kristin K Brown, et al.
ACS Chemical Biology|April 24, 2024
mRNA Display Identifies Potent, Paralog-Selective Peptidic Ligands for ARID1BGregor S Cremosnik, Yannick Mesrouze, Patrik Zueger, et al.
Nature|July 13, 2022
Structure of the MRAS-SHOC2-PP1C phosphatase complexZachary J Hauseman, Michelle Fodor, Anxhela Dhembi, et al.
Nature Medicine|May 10, 2019
The landscape of cancer cell line metabolismHaoxin Li, Shaoyang Ning, Mahmoud Ghandi, et al.
Nature Communications|December 2, 2025
Identification and characterization of binders to a cryptic and functional pocket in KRASKim S Beyer, Jessica Klein, Stéphanie Katz, et al.
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